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    ins-26 INSulin related [ Caenorhabditis elegans ]

    Gene ID: 173268, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ins-26
    Official Full Name
    INSulin related
    Primary source
    WormBase:WBGene00002109
    Locus tag
    CELE_ZC334.1
    See related
    AllianceGenome:WB:WBGene00002109
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable hormone activity. Predicted to be involved in signal transduction. Predicted to be located in extracellular region. Is expressed in several structures, including coelomocyte; head muscle; intestine; neurons; and ventral nerve cord. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ins-26 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    2
    Sequence:
    Chromosome: I; NC_003279.8 (14037151..14037777, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene INSulin related Neighboring gene INSulin related Neighboring gene Nuclear Hormone Receptor family Neighboring gene ncRNA Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Chronic vs acute manipulations reveal degeneracy in a thermosensory neuron network. Yeon J, et al. MicroPubl Biol, 2021 Jan 15. PMID 33474527, Free PMC Article
    2. Feeding state-dependent regulation of developmental plasticity via CaMKI and neuroendocrine signaling. Neal SJ, et al. Elife, 2015 Sep 3. PMID 26335407, Free PMC Article
    3. Ins-4 and daf-28 function redundantly to regulate C. elegans L1 arrest. Chen Y, et al. Dev Biol, 2014 Oct 15. PMID 25128585
    4. Cell-Autonomous and Non-Cell-Autonomous Regulation of a Feeding State-Dependent Chemoreceptor Gene via MEF-2 and bHLH Transcription Factors. Gruner M, et al. PLoS Genet, 2016 Aug. PMID 27487365, Free PMC Article
    5. Early pheromone perception remodels neurodevelopment and accelerates neurodegeneration in adult C. elegans. Peng JY, et al. Cell Rep, 2023 Jun 27. PMID 37289584

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables hormone activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    INSulin related
    NP_493445.1
    • Product from WormBase gene class ins;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      14037151..14037777 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_061044.6 → NP_493445.1  INSulin related [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_493445.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9XUI9
    Nucleotide Protein
    Heading Accession and Version

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