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    coa-6 Cytochrome c oxidase assembly factor 6 homolog;PRORP domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 172906, updated on 9-Dec-2024

    Summary

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    Official Symbol
    coa-6
    Official Full Name
    Cytochrome c oxidase assembly factor 6 homolog;PRORP domain-containing protein
    Primary source
    WormBase:WBGene00013893
    Locus tag
    CELE_ZC434.7
    See related
    AllianceGenome:WB:WBGene00013893
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in mitochondrial ATP synthesis coupled electron transport and respiratory chain complex IV assembly. Predicted to be part of respiratory chain complex IV. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 54. Orthologous to human PRORP (protein only RNase P catalytic subunit). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See coa-6 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    10
    Sequence:
    Chromosome: I; NC_003279.8 (10345738..10348065)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene DUF3421 domain-containing protein Neighboring gene glutamate--tRNA ligase Neighboring gene Nicastrin Neighboring gene putative arginine kinase ZC434.8 Neighboring gene ShKT domain-containing protein Neighboring gene Specificity protein transcription factor 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in mitochondrial ATP synthesis coupled electron transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in respiratory chain complex IV assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in respiratory chain complex IV assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of respiratory chain complex IV IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Cytochrome c oxidase assembly factor 6 homolog;PRORP domain-containing protein
    NP_001366833.1
    • Confirmed by transcript evidence
    NP_001367155.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      10345738..10348065
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001381194.1 → NP_001367155.1  Cytochrome c oxidase assembly factor 6 homolog [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A5JYU1
      Conserved Domains (1) summary
      pfam02297
      Location:9 → 73
      COX6B; Cytochrome oxidase c subunit VIb

    2. NM_001381195.2 → NP_001366833.1  PRORP domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q23317
      Conserved Domains (1) summary
      cl28905
      Location:311 → 411
      PIN_SF; PIN (PilT N terminus) domain: Superfamily
    Nucleotide Protein
    Heading Accession and Version

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