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    madf-9 MADF domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 191167, updated on 9-Dec-2024

    Summary

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    Official Symbol
    madf-9
    Official Full Name
    MADF domain-containing protein
    Primary source
    WormBase:WBGene00022608
    Locus tag
    CELE_ZC416.1
    See related
    AllianceGenome:WB:WBGene00022608
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See madf-9 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    5
    Sequence:
    Chromosome: IV; NC_003282.8 (3637079..3640466)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Choline O-acetyltransferase Neighboring gene Vesicular acetylcholine transporter unc-17 Neighboring gene Cysteine-rich transmembrane CYSTM domain-containing protein Neighboring gene ncRNA Neighboring gene Cysteine-rich transmembrane CYSTM domain-containing protein Neighboring gene Protein phosphatase 1 regulatory subunit

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. H3K9me selectively blocks transcription factor activity and ensures differentiated tissue integrity. Methot SP, et al. Nat Cell Biol, 2021 Nov. PMID 34737442, Free PMC Article
    2. C. elegans ORFeome version 1.1: experimental verification of the genome annotation and resource for proteome-scale protein expression. Reboul J, et al. Nat Genet, 2003 May. PMID 12679813
    3. SH3 interactome conserves general function over specific form. Xin X, et al. Mol Syst Biol, 2013. PMID 23549480, Free PMC Article
    4. Extensive rewiring and complex evolutionary dynamics in a C. elegans multiparameter transcription factor network. Reece-Hoyes JS, et al. Mol Cell, 2013 Jul 11. PMID 23791784, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of transcription regulator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    MADF domain-containing protein
    NP_500389.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      3637079..3640466
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_067988.4 → NP_500389.2  MADF domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_500389.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2KZH8
      Conserved Domains (1) summary
      smart00595
      Location:52 → 136
      MADF; subfamily of SANT domain
    Nucleotide Protein
    Heading Accession and Version

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