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    exoc-8 Exocyst component Exo84 C-terminal domain-containing protein;PH domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 173320, updated on 9-Dec-2024

    Summary

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    Official Symbol
    exoc-8
    Official Full Name
    Exocyst component Exo84 C-terminal domain-containing protein;PH domain-containing protein
    Primary source
    WormBase:WBGene00013687
    Locus tag
    CELE_Y105E8B.2
    See related
    AllianceGenome:WB:WBGene00013687
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in Golgi to plasma membrane transport and protein localization. Predicted to be part of exocyst. Is expressed in PVDL and PVDR. Orthologous to human EXOC8 (exocyst complex component 8). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See exoc-8 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    8
    Sequence:
    Chromosome: I; NC_003279.8 (14634453..14642568, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Acyl-CoA dehydrogenase Neighboring gene Tropomyosin;Tropomyosin isoforms a/b/d/f;Tropomyosin isoforms c/e Neighboring gene ncRNA Neighboring gene Protein AF-9 homolog Neighboring gene BTB and MATH domain-containing protein 40

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Exocyst subunits Exo70 and Exo84 cooperate with small GTPases to regulate behavior and endocytic trafficking in C. elegans. Jiu Y, et al. PLoS One, 2012. PMID 22389680, Free PMC Article
    2. RAB-10-Dependent Membrane Transport Is Required for Dendrite Arborization. Zou W, et al. PLoS Genet, 2015. PMID 26394140, Free PMC Article
    3. RAL-1 signaling regulates lipid composition in C. elegans. Wu Y, et al. MicroPubl Biol, 2024. PMID 38454952, Free PMC Article
    4. RAB-10 Regulates Dendritic Branching by Balancing Dendritic Transport. Taylor CA, et al. PLoS Genet, 2015 Dec. PMID 26633194, Free PMC Article
    5. The cell cortex-localized protein CHDP-1 is required for dendritic development and transport in C. elegans neurons. Zhao T, et al. PLoS Genet, 2022 Sep. PMID 36126047, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in Golgi to plasma membrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in exocytosis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein localization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of exocyst IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of exocyst IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of exocyst ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Exocyst component Exo84 C-terminal domain-containing protein;PH domain-containing protein
    NP_001021702.1
    • Confirmed by transcript evidence
    NP_001359664.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      14634453..14642568 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001026531.6 → NP_001021702.1  Exocyst component Exo84 C-terminal domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001021702.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95Q35
      Conserved Domains (3) summary
      pfam08700
      Location:9 → 98
      Vps51; Vps51/Vps67
      pfam16528
      Location:306 → 467
      Exo84_C; Exocyst component 84 C-terminal
      cl17171
      Location:140 → 252
      PH-like; Pleckstrin homology-like domain

    2. NM_001373669.4 → NP_001359664.1  PH domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7YTV2
      Conserved Domains (2) summary
      pfam08700
      Location:9 → 98
      Vps51; Vps51/Vps67
      cl17171
      Location:140 → 252
      PH-like; Pleckstrin homology-like domain
    Nucleotide Protein
    Heading Accession and Version

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