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    MIR99AHG mir-99a-let-7c cluster host gene [ Homo sapiens (human) ]

    Gene ID: 388815, updated on 10-Dec-2024

    Summary

    Official Symbol
    MIR99AHGprovided by HGNC
    Official Full Name
    mir-99a-let-7c cluster host geneprovided by HGNC
    Primary source
    HGNC:HGNC:1274
    See related
    Ensembl:ENSG00000215386 MIM:615964; AllianceGenome:HGNC:1274
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    MONC; DILA1; C21orf34; C21orf35; LINC00478
    Expression
    Broad expression in brain (RPKM 3.1), ovary (RPKM 3.0) and 17 other tissues See more
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See MIR99AHG in Genome Data Viewer
    Location:
    21q21.1
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 21 NC_000021.9 (16070488..16631727)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 21 NC_060945.1 (14425873..14987212)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 21 NC_000021.8 (17442808..18004046)

    Chromosome 21 - NC_000021.9Genomic Context describing neighboring genes Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr21:17125262-17125887 Neighboring gene RNA binding protein with multiple splicing-like pseudogene Neighboring gene Sharpr-MPRA regulatory region 15533 Neighboring gene ubiquitin specific peptidase 25 Neighboring gene NANOG hESC enhancer GRCh37_chr21:17357279-17357780 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr21:17364583-17365782 Neighboring gene RNA, U6 small nuclear 426, pseudogene Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:17517702-17518202 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:17518203-17518703 Neighboring gene VDAC2 pseudogene 1 Neighboring gene Sharpr-MPRA regulatory region 14289 Neighboring gene H3K27ac hESC enhancer GRCh37_chr21:17566156-17566916 Neighboring gene ribosomal protein S26 pseudogene 5 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr21:17613639-17614628 Neighboring gene VISTA enhancer hs1304 Neighboring gene small nucleolar RNA, C/D box 74B Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:17935956-17936510 Neighboring gene VISTA enhancer hs1441 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr21:17959347-17960041 Neighboring gene microRNA let-7c Neighboring gene microRNA 99a Neighboring gene microRNA 125b-2 Neighboring gene RNA, U1 small nuclear 98, pseudogene Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr21:18166790-18167989 Neighboring gene uncharacterized LOC124904998

    Genomic regions, transcripts, and products

    Expression

    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Phenotypes

    EBI GWAS Catalog

    Description
    A genome wide association study (GWAS) providing evidence of an association between common genetic variants and late radiotherapy toxicity.
    EBI GWAS Catalog
    Family-based genome-wide association scan of attention-deficit/hyperactivity disorder.
    EBI GWAS Catalog
    Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease.
    EBI GWAS Catalog
    Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
    EBI GWAS Catalog

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Other Names

    • Cyclin D1-interacting long noncoding RNA 1
    • long intergenic non-protein coding RNA 478
    • megakaryocytic oncogenic non-coding RNA
    • mir-99a-let-7c cluster host gene (non-protein coding)

    Clone Names

    • FLJ38295

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_027790.3 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AK095614, AP000473, KF511330
    2. NR_027791.3 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AP000473, BC130602, CF135139, KF511330
      Related
      ENST00000657710.3
    3. NR_111004.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AP000473, CN313455, KF511330
      Related
      ENST00000660908.2
    4. NR_111005.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AF486622, AP000473, AP001344, KF511330
      Related
      ENST00000656642.3
    5. NR_136541.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AP000473, AP000962, AP001172, AP001343, AP001344, AP001346
      Related
      ENST00000698109.1
    6. NR_136542.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AP000473, AP000962, AP001172, AP001343, AP001344, AP001346, KF511330
      Related
      ENST00000698110.1
    7. NR_136543.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AP000473, AP000962, AP001172, AP001343, AP001346, KF511330
      Related
      ENST00000670980.2
    8. NR_136544.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AP000473, AP000962, AP001172, KF454942, KF511330
      Related
      ENST00000664445.2
    9. NR_136545.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AP000473, AP000962, AP001172, KF454942, KF511330
      Related
      ENST00000453910.8
    10. NR_136546.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AP000473, AP000962, AP001172, KF454942, KF511330
    11. NR_136547.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AP000473, AP000962, KF511330
    12. NR_136548.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AP000473, AP000962, KF511330
      Related
      ENST00000698096.1
    13. NR_136549.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AP000473, AP000962, KF511330
      Related
      ENST00000661939.2
    14. NR_136550.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AP000473, AP000962, AP001172, KF511330
      Related
      ENST00000657520.3
    15. NR_136551.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AP000473, AP000962, AP001172, AP001343, AP001346, KF511330
      Related
      ENST00000697942.2
    16. NR_136552.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AP000473, AP000962, AP001172, AP001343, AP001346, KF511330
      Related
      ENST00000698166.1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000021.9 Reference GRCh38.p14 Primary Assembly

      Range
      16070488..16631727
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060945.1 Alternate T2T-CHM13v2.0

      Range
      14425873..14987212
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)