Aida axin interactor, dorsalization associated [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Aidaprovided by RGD
Official Full Name: axin interactor, dorsalization associatedprovided by RGD
Primary source: RGD:1592746
See related: EnsemblRapid:ENSRNOG00000058805 AllianceGenome:RGD:1592746
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable phosphatidylinositol binding activity and protein domain specific binding activity. Predicted to be involved in determination of ventral identity; negative regulation of JNK cascade; and negative regulation of protein-containing complex assembly. Predicted to act upstream of or within negative regulation of JUN kinase activity and regulation of protein-containing complex assembly. Predicted to be located in cytoplasm. Predicted to be active in membrane. Orthologous to human AIDA (axin interactor, dorsalization associated). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Lung (RPKM 131.0), Spleen (RPKM 127.0) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 13q26

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	13	NC_086031.1 (97471931..97499531)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	13	NC_051348.1 (94940311..94967920)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	13	NC_005112.4 (101698096..101724928)

Chromosome 13 - NC_086031.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

BI278943 (e-PCR)
- UniSTS:244485

RH134995 (e-PCR)
- UniSTS:218272

RH143707 (e-PCR)
- UniSTS:232953

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables phosphatidylinositol binding	IBA Inferred from Biological aspect of Ancestor more info
enables protein domain specific binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in determination of ventral identity	IBA Inferred from Biological aspect of Ancestor more info
involved_in negative regulation of JNK cascade	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within negative regulation of JUN kinase activity	ISO Inferred from Sequence Orthology more info
NOT involved_in negative regulation of Wnt signaling pathway	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of protein-containing complex assembly	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within regulation of protein-containing complex assembly	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
is_active_in membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: axin interactor, dorsalization-associated protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.