Cox8b cytochrome c oxidase, subunit VIIIb [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Cox8bprovided by RGD
Official Full Name: cytochrome c oxidase, subunit VIIIbprovided by RGD
Primary source: RGD:2386
See related: EnsemblRapid:ENSRNOG00000073367 AllianceGenome:RGD:2386
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: CCO8A; Cox8h; COXVIII-H
Summary: Predicted to enable cytochrome-c oxidase activity. Involved in response to xenobiotic stimulus. Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex IV. Predicted to be active in mitochondrion. Used to study obesity. [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Heart (RPKM 12462.9), Muscle (RPKM 9124.6) and 1 other tissue See more
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Genomic context

Location:: 1q41

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (205406813..205408273, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (195977183..195978643, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (213648787..213650247, complement)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables cytochrome-c oxidase activity	TAS Traceable Author Statement more info	PubMed

Process	Evidence Code	Pubs
involved_in mitochondrial electron transport, cytochrome c to oxygen	TAS Traceable Author Statement more info	PubMed
involved_in proton transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in response to xenobiotic stimulus	IEP Inferred from Expression Pattern more info	PubMed

Component	Evidence Code	Pubs
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
part_of respiratory chain complex IV	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: cytochrome c oxidase subunit 8B, mitochondrial

Names: Cytochrom c oxidase subunit VIII-H (heart/muscle); Cytochrome c oxidase subunit VIII-H (heart/muscle); cytochrome c oxidase polypeptide VIII-heart; cytochrome c oxidase subunit 8-1; cytochrome c oxidase subunit 8H; cytochrome c oxidase, subunit 8B; cytochrome c oxidase, subunit VIIIb, muscle

NP_036918.2

EC 7.1.1.9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.