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    Tnrc18 trinucleotide repeat containing 18 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 304302, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Tnrc18provided by RGD
    Official Full Name
    trinucleotide repeat containing 18provided by RGD
    Primary source
    RGD:1307540
    See related
    EnsemblRapid:ENSRNOG00000024482 AllianceGenome:RGD:1307540
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Zfp469
    Summary
    Predicted to enable chromatin binding activity. Predicted to be located in cytosol; mitochondrion; and nucleus. Orthologous to human TNRC18 (trinucleotide repeat containing 18). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Kidney (RPKM 63.8), Adrenal (RPKM 48.2) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Tnrc18 in Genome Data Viewer
    Location:
    12p11
    Exon count:
    31
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (16868930..16965224)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (11755394..11851717)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (13807819..13912295)

    Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene F-box and leucine-rich repeat protein 18 Neighboring gene uncharacterized LOC108352424 Neighboring gene uncharacterized LOC120095837 Neighboring gene solute carrier family 29 member 4 Neighboring gene WD repeat domain, phosphoinositide interacting 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables chromatin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nuclear membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nuclear membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    trinucleotide repeat-containing gene 18 protein
    Names
    zinc finger protein 469

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107123.2 → NP_001100593.2  trinucleotide repeat-containing gene 18 protein

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012
      UniProtKB/TrEMBL
      A6K1P2, D3ZKV7
      Related
      ENSRNOP00000034125.7, ENSRNOT00000038203.8
      Conserved Domains (3) summary
      PHA03247
      Location:331 → 589
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:2222 → 2472
      PHA03307; transcriptional regulator ICP4; Provisional
      cd04714
      Location:2748 → 2892
      BAH_BAHCC1; BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. BAHCC1 stands for BAH domain and coiled-coil containing 1. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the ...

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086030.1 Reference GRCr8

      Range
      16868930..16965224
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063271267.1 → XP_063127337.1  trinucleotide repeat-containing gene 18 protein isoform X10

    2. XM_039089375.2 → XP_038945303.1  trinucleotide repeat-containing gene 18 protein isoform X5

      UniProtKB/TrEMBL
      A6K1P3
      Conserved Domains (5) summary
      PHA03247
      Location:383 → 641
      PHA03247; large tegument protein UL36; Provisional
      PRK10263
      Location:2262 → 2467
      PRK10263; DNA translocase FtsK; Provisional
      cd04714
      Location:2744 → 2888
      BAH_BAHCC1; BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. BAHCC1 stands for BAH domain and coiled-coil containing 1. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the ...
      NF033930
      Location:1089 → 1165
      pneumo_PspA; pneumococcal surface protein A
      cl02573
      Location:2204 → 2270
      Tudor_SF; Tudor domain superfamily

    3. XM_039089379.2 → XP_038945307.1  trinucleotide repeat-containing gene 18 protein isoform X9

      Conserved Domains (2) summary
      PHA03247
      Location:331 → 589
      PHA03247; large tegument protein UL36; Provisional
      NF033930
      Location:1036 → 1112
      pneumo_PspA; pneumococcal surface protein A

    4. XM_039089371.2 → XP_038945299.1  trinucleotide repeat-containing gene 18 protein isoform X1

      UniProtKB/TrEMBL
      A0A8I6AKW0, A6K1P2
      Related
      ENSRNOP00000093862.1, ENSRNOT00000117077.2
      Conserved Domains (5) summary
      PHA03247
      Location:383 → 641
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:2274 → 2524
      PHA03307; transcriptional regulator ICP4; Provisional
      cd04714
      Location:2800 → 2944
      BAH_BAHCC1; BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. BAHCC1 stands for BAH domain and coiled-coil containing 1. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the ...
      NF033930
      Location:1089 → 1165
      pneumo_PspA; pneumococcal surface protein A
      cl02573
      Location:2204 → 2270
      Tudor_SF; Tudor domain superfamily

    5. XM_039089373.2 → XP_038945301.1  trinucleotide repeat-containing gene 18 protein isoform X3

      UniProtKB/TrEMBL
      A6K1P2
      Conserved Domains (5) summary
      PHA03247
      Location:383 → 641
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:2236 → 2486
      PHA03307; transcriptional regulator ICP4; Provisional
      cd04714
      Location:2762 → 2906
      BAH_BAHCC1; BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. BAHCC1 stands for BAH domain and coiled-coil containing 1. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the ...
      NF033930
      Location:1089 → 1165
      pneumo_PspA; pneumococcal surface protein A
      cl02573
      Location:2166 → 2232
      Tudor_SF; Tudor domain superfamily

    6. XM_039089374.2 → XP_038945302.1  trinucleotide repeat-containing gene 18 protein isoform X4

      UniProtKB/TrEMBL
      A0A8I6A586
      Conserved Domains (4) summary
      PHA03247
      Location:383 → 641
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:2231 → 2481
      PHA03307; transcriptional regulator ICP4; Provisional
      cd04714
      Location:2757 → 2901
      BAH_BAHCC1; BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. BAHCC1 stands for BAH domain and coiled-coil containing 1. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the ...
      cl02573
      Location:2161 → 2227
      Tudor_SF; Tudor domain superfamily

    7. XM_063271265.1 → XP_063127335.1  trinucleotide repeat-containing gene 18 protein isoform X7

    8. XM_039089372.2 → XP_038945300.1  trinucleotide repeat-containing gene 18 protein isoform X2

      UniProtKB/TrEMBL
      A6K1P2
      Conserved Domains (5) summary
      PHA03247
      Location:383 → 641
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:2273 → 2523
      PHA03307; transcriptional regulator ICP4; Provisional
      cd04714
      Location:2799 → 2943
      BAH_BAHCC1; BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. BAHCC1 stands for BAH domain and coiled-coil containing 1. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the ...
      NF033930
      Location:1088 → 1164
      pneumo_PspA; pneumococcal surface protein A
      cl02573
      Location:2203 → 2269
      Tudor_SF; Tudor domain superfamily

    9. XM_063271266.1 → XP_063127336.1  trinucleotide repeat-containing gene 18 protein isoform X8

      Related
      ENSRNOP00000086100.1, ENSRNOT00000098287.2

    10. XM_039089376.2 → XP_038945304.1  trinucleotide repeat-containing gene 18 protein isoform X6

      UniProtKB/TrEMBL
      A6K1P2
      Conserved Domains (4) summary
      PHA03247
      Location:309 → 567
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:2200 → 2450
      PHA03307; transcriptional regulator ICP4; Provisional
      cd04714
      Location:2726 → 2870
      BAH_BAHCC1; BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. BAHCC1 stands for BAH domain and coiled-coil containing 1. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the ...
      cl02573
      Location:2130 → 2196
      Tudor_SF; Tudor domain superfamily
    Nucleotide Protein Strain
    Heading Accession and Version

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