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    Cfap141 cilia and flagella associated protein 141 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 499656, updated on 27-Dec-2024

    Summary

    Official Symbol
    Cfap141provided by RGD
    Official Full Name
    cilia and flagella associated protein 141provided by RGD
    Primary source
    RGD:1564171
    See related
    EnsemblRapid:ENSRNOG00000037406 AllianceGenome:RGD:1564171
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1564171
    Summary
    Predicted to be involved in flagellated sperm motility. Predicted to be located in axonemal microtubule. Predicted to be active in axonemal A tubule inner sheath and sperm flagellum. Orthologous to human CFAP141 (cilia and flagella associated protein 141). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 135.2), Thymus (RPKM 59.2) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Cfap141 in Genome Data Viewer
    Location:
    2q34
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (177805290..177808324)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (175507628..175510662)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (189413966..189417000)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103691621 Neighboring gene ubiquitin associated protein 2-like Neighboring gene NS5A transactivated protein 4 Neighboring gene microRNA 190b Neighboring gene tropomyosin 3 Neighboring gene transfer RNA proline (anticodon AGG) 20 Neighboring gene nucleoporin 210-like

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in flagellated sperm motility IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in flagellated sperm motility ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in axonemal A tubule inner sheath ISO
    Inferred from Sequence Orthology
    more info
     
    located_in axonemal microtubule ISO
    Inferred from Sequence Orthology
    more info
     
    located_in sperm flagellum IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in sperm flagellum ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    cilia- and flagella-associated protein 141
    Names
    uncharacterized protein C1orf189 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109186.1NP_001102656.1  cilia- and flagella-associated protein 141

      See identical proteins and their annotated locations for NP_001102656.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473976
      UniProtKB/TrEMBL
      A6J6J3, D3ZLY5
      Related
      ENSRNOP00000053442.4, ENSRNOT00000056603.6
      Conserved Domains (1) summary
      pfam15104
      Location:15100
      DUF4558; Domain of unknown function (DUF4558)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      177805290..177808324
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)