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    Bpifa5 BPI fold containing family A, member 5 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 311559, updated on 27-Nov-2024

    Summary

    Official Symbol
    Bpifa5provided by RGD
    Official Full Name
    BPI fold containing family A, member 5provided by RGD
    Primary source
    RGD:1559748
    See related
    EnsemblRapid:ENSRNOG00000013908 AllianceGenome:RGD:1559748
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Splunc5; RGD1559748
    Summary
    Predicted to enable lipid binding activity. Predicted to be involved in several processes, including defense response to symbiont; negative regulation of single-species biofilm formation in or on host organism; and surfactant homeostasis. Predicted to be active in extracellular space. Orthologous to several human genes including BPIFA1 (BPI fold containing family A member 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward (RPKM 29.0) See more
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    Genomic context

    See Bpifa5 in Genome Data Viewer
    Location:
    3q41
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (163106258..163113039)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (142646103..142652884)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (149643481..149649398)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134486304 Neighboring gene BPI fold containing family A, member 1 Neighboring gene BPI fold containing family B, member 1 Neighboring gene BPI fold containing family B, member 5

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables lipid binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in antibacterial humoral response IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in antimicrobial humoral immune response mediated by antimicrobial peptide IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in immune response in nasopharyngeal-associated lymphoid tissue IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in innate immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in negative regulation of single-species biofilm formation in or on host organism IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in surfactant homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    palate lung and nasal carcinoma-like protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107792.2NP_001101262.1  palate lung and nasal carcinoma-like protein precursor

      See identical proteins and their annotated locations for NP_001101262.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003
      UniProtKB/TrEMBL
      A6KHX7, D3ZWC2
      Related
      ENSRNOP00000020713.4, ENSRNOT00000020713.6
      Conserved Domains (1) summary
      pfam01273
      Location:76248
      LBP_BPI_CETP; LBP / BPI / CETP family, N-terminal domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      163106258..163113039
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039105071.2XP_038960999.2  palate lung and nasal carcinoma-like protein isoform X1

      UniProtKB/TrEMBL
      A0A8I6AKM9
      Related
      ENSRNOP00000093753.1, ENSRNOT00000104063.2