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    APK2B protein kinase 2B [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 814810, updated on 18-Sep-2024

    Summary

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    Official Symbol
    APK2B
    Official Full Name
    protein kinase 2B
    Primary source
    TAIR:AT2G02800
    Locus tag
    AT2G02800
    See related
    Araport:AT2G02800
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    Kin2; kinase 2; protein kinase 2B; PROTEIN KINASE 2B; T20F6.6; T20F6_6
    Summary
    Encodes protein kinase APK2b.
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    Genomic context

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    See APK2B in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    7
    Sequence:
    Chromosome: 2; NC_003071.7 (795515..799591, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene IQ-domain 29 Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene UDP-galactose transporter 1 Neighboring gene myb domain protein 88

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Protein N-acylation overrides differing targeting signals. Stael S, et al. FEBS Lett, 2011 Feb 4. PMID 21219905, Free PMC Article
    2. High-throughput protein localization in Arabidopsis using Agrobacterium-mediated transient expression of GFP-ORF fusions. Koroleva OA, et al. Plant J, 2005 Jan. PMID 15610358
    3. Differential binding of calmodulin-related proteins to their targets revealed through high-density Arabidopsis protein microarrays. Popescu SC, et al. Proc Natl Acad Sci U S A, 2007 Mar 13. PMID 17360592, Free PMC Article
    4. A high content in lipid-modified peripheral proteins and integral receptor kinases features in the arabidopsis plasma membrane proteome. Marmagne A, et al. Mol Cell Proteomics, 2007 Nov. PMID 17644812
    5. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_126335.6
    NM_201674.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    NOT located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm HDA PubMed 
    located_in nucleus HDA PubMed 
    located_in plasma membrane HDA PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein kinase 2B
    NP_178383.1
    • protein kinase 2B (APK2B); FUNCTIONS IN: protein serine/threonine kinase activity, protein kinase activity, kinase activity, ATP binding; INVOLVED IN: protein amino acid phosphorylation; LOCATED IN: nucleus, plasma membrane, cytoplasm; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine-threonine/tyrosine-protein kinase (InterPro:IPR001245), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: protein kinase 2A (TAIR:AT1G14370.1); Has 113663 Blast hits to 112197 proteins in 3955 species: Archae - 101; Bacteria - 13127; Metazoa - 42007; Fungi - 9244; Plants - 32902; Viruses - 370; Other Eukaryotes - 15912 (source: NCBI BLink).
    NP_973403.1
    • protein kinase 2B (APK2B); FUNCTIONS IN: protein serine/threonine kinase activity, protein kinase activity, kinase activity, ATP binding; INVOLVED IN: protein amino acid phosphorylation; LOCATED IN: nucleus, plasma membrane, cytoplasm; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine-threonine/tyrosine-protein kinase (InterPro:IPR001245), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: protein kinase 2A (TAIR:AT1G14370.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      795515..799591 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_201674.2 → NP_973403.1  protein kinase 2B [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_973403.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O49840, Q8GYU1
      UniProtKB/TrEMBL
      A0A178VQA1, A0A5S9WX04
      Conserved Domains (1) summary
      cd14066
      Location:89 → 366
      STKc_IRAK; Catalytic domain of the Serine/Threonine kinases, Interleukin-1 Receptor Associated Kinases and related STKs

    2. NM_126335.6 → NP_178383.1  protein kinase 2B [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_178383.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O49840, Q8GYU1
      UniProtKB/TrEMBL
      A0A178VQA1, A0A5S9WX04
      Conserved Domains (1) summary
      cd14066
      Location:89 → 366
      STKc_IRAK; Catalytic domain of the Serine/Threonine kinases, Interleukin-1 Receptor Associated Kinases and related STKs
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O49840.1

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