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    GPT UDP-glcnac-adolichol phosphate glcnac-1-p-transferase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 818747, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GPT
    Official Full Name
    UDP-glcnac-adolichol phosphate glcnac-1-p-transferase
    Primary source
    TAIR:AT2G41490
    Locus tag
    AT2G41490
    See related
    Araport:AT2G41490
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T26J13.8; T26J13_8; UDP-glcnac-adolichol phosphate glcnac-1-p-transferase
    Summary
    UDP-GlcNAc:dolichol phosphate N-acetylglucosamine-1-phosphate transferase
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    Genomic context

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    See GPT in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    11
    Sequence:
    Chromosome: 2; NC_003071.7 (17301572..17304211)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Embryo-specific protein 3, (ATS3) Neighboring gene peroxidase superfamily protein Neighboring gene WD-40 repeat family protein / small nuclear ribonucleoprotein Prp4p-like protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene cytokinin oxidase/dehydrogenase 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Overexpression of a gene that encodes the first enzyme in the biosynthesis of asparagine-linked glycans makes plants resistant to tunicamycin and obviates the tunicamycin-induced unfolded protein response. Koizumi N, et al. Plant Physiol, 1999 Oct. PMID 10517826, Free PMC Article
    2. Border control--a membrane-linked interactome of Arabidopsis. Jones AM, et al. Science, 2014 May 16. PMID 24833385
    3. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_129712.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in dolichol-linked oligosaccharide biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    UDP-glcnac-adolichol phosphate glcnac-1-p-transferase
    NP_565950.1
    • UDP-glcnac-adolichol phosphate glcnac-1-p-transferase (GPT); CONTAINS InterPro DOMAIN/s: Glycosyl transferase, family 4, conserved region (InterPro:IPR018481); BEST Arabidopsis thaliana protein match is: Glycosyl transferase family 4 protein (TAIR:AT3G57220.1); Has 6620 Blast hits to 6619 proteins in 2189 species: Archae - 133; Bacteria - 5202; Metazoa - 126; Fungi - 129; Plants - 61; Viruses - 0; Other Eukaryotes - 969 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      17301572..17304211
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_129712.3 → NP_565950.1  UDP-glcnac-adolichol phosphate glcnac-1-p-transferase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565950.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VV44, A0A5S9X637, O22211, Q8LG07, Q9S7A5
      Conserved Domains (1) summary
      cd06855
      Location:99 → 382
      GT_GPT_euk; UDP-GlcNAc:dolichol-P GlcNAc-1-P transferase (GPT) catalyzes the transfer of GlcNAc-1-P from UDP-GlcNAc to dolichol-P to form GlcNAc-P-P-dolichol. The reaction is the first step in the assembly of dolichol-linked oligosaccharide intermediates and is ...
    Nucleotide Protein
    Heading Accession and Version

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