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    PMM phosphomannomutase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 819187, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PMM
    Official Full Name
    phosphomannomutase
    Primary source
    TAIR:AT2G45790
    Locus tag
    AT2G45790
    See related
    Araport:AT2G45790
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATPMM; F4I18.23; phosphomannomutase; PHOSPHOMANNOMUTASE
    Summary
    encodes a phosphomannomutase, involved in ascorbate biosynthesis
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    Genomic context

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    See PMM in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    10
    Sequence:
    Chromosome: 2; NC_003071.7 (18855675..18858018)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene signal recognition particle receptor protein, chloroplast (FTSY) Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene GATA type zinc finger transcription factor family protein Neighboring gene DEA(D/H)-box RNA helicase family protein Neighboring gene Remorin family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. CML10, a variant of calmodulin, modulates ascorbic acid synthesis. Cho KM, et al. New Phytol, 2016 Jan. PMID 26315131
    2. Molecular and functional analysis of phosphomannomutase (PMM) from higher plants and genetic evidence for the involvement of PMM in ascorbic acid biosynthesis in Arabidopsis and Nicotiana benthamiana. Qian W, et al. Plant J, 2007 Feb. PMID 17217471
    3. Proximity labeling of protein complexes and cell-type-specific organellar proteomes in Arabidopsis enabled by TurboID. Mair A, et al. Elife, 2019 Sep 19. PMID 31535972, Free PMC Article
    4. Proteomic profiling of tandem affinity purified 14-3-3 protein complexes in Arabidopsis thaliana. Chang IF, et al. Proteomics, 2009 Jun. PMID 19452453, Free PMC Article
    5. A proteomic strategy for global analysis of plant protein complexes. Aryal UK, et al. Plant Cell, 2014 Oct. PMID 25293756, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_130142.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables phosphomannomutase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables phosphomannomutase activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in GDP-mannose biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within L-ascorbic acid biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol HDA PubMed 

    General protein information

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    Preferred Names
    phosphomannomutase
    NP_182103.1
    • phosphomannomutase (PMM); FUNCTIONS IN: protein binding, phosphomannomutase activity; INVOLVED IN: L-ascorbic acid biosynthetic process, response to salt stress, mannose biosynthetic process; LOCATED IN: cytoplasm; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Eukaryotic phosphomannomutase (InterPro:IPR005002), HAD-superfamily hydrolase, subfamily IIB (InterPro:IPR006379); Has 1083 Blast hits to 1081 proteins in 282 species: Archae - 1; Bacteria - 92; Metazoa - 201; Fungi - 171; Plants - 223; Viruses - 0; Other Eukaryotes - 395 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      18855675..18858018
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_130142.4 → NP_182103.1  phosphomannomutase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_182103.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O80840, Q1W379
      UniProtKB/TrEMBL
      A0A178W2D7, A0A5S9X7B1, A0A7G2EHQ0
      Conserved Domains (1) summary
      PLN02423
      Location:1 → 245
      PLN02423; phosphomannomutase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O80840.1

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