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    TRN1 transportin 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 816198, updated on 18-Sep-2024

    Summary

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    Official Symbol
    TRN1
    Official Full Name
    transportin 1
    Primary source
    TAIR:AT2G16950
    Locus tag
    AT2G16950
    See related
    Araport:AT2G16950
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATTRN1; F12A24.13; F12A24_13; transportin 1; TRANSPORTIN 1
    Summary
    Nuclear import receptor for AtGRP7.
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    Genomic context

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    See TRN1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    29
    Sequence:
    Chromosome: 2; NC_003071.7 (7353773..7361256)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Ribosomal protein L27 family protein Neighboring gene Splicing factor, CC1-like protein Neighboring gene transportin Neighboring gene ARM repeat superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of potential cargo proteins of transportin protein AtTRN1 in Arabidopsis thaliana. Yan B, et al. Plant Cell Rep, 2016 Mar. PMID 26650834
    2. TRANSPORTIN1 Promotes the Association of MicroRNA with ARGONAUTE1 in Arabidopsis. Cui Y, et al. Plant Cell, 2016 Oct. PMID 27662897, Free PMC Article
    3. Arabidopsis transportin1 is the nuclear import receptor for the circadian clock-regulated RNA-binding protein AtGRP7. Ziemienowicz A, et al. Plant Mol Biol, 2003 Sep. PMID 14756317
    4. A DEK domain-containing protein modulates chromatin structure and function in Arabidopsis. Waidmann S, et al. Plant Cell, 2014 Nov. PMID 25387881, Free PMC Article
    5. Targeted interactomics reveals a complex core cell cycle machinery in Arabidopsis thaliana. Van Leene J, et al. Mol Syst Biol, 2010 Aug 10. PMID 20706207, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001036282.2
    NM_127248.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables nucleocytoplasmic carrier activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables small GTPase binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within import into nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in protein import into nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    transportin 1
    NP_001031359.1
    • transportin 1 (TRN1); CONTAINS InterPro DOMAIN/s: HEAT (InterPro:IPR000357), Importin-beta, N-terminal (InterPro:IPR001494), Armadillo-like helical (InterPro:IPR011989), Armadillo-type fold (InterPro:IPR016024); BEST Arabidopsis thaliana protein match is: ARM repeat superfamily protein (TAIR:AT2G16960.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_179287.3
    • transportin 1 (TRN1); CONTAINS InterPro DOMAIN/s: HEAT (InterPro:IPR000357), Importin-beta, N-terminal (InterPro:IPR001494), Armadillo-like helical (InterPro:IPR011989), Armadillo-type fold (InterPro:IPR016024); BEST Arabidopsis thaliana protein match is: ARM repeat superfamily protein (TAIR:AT2G16960.1); Has 1831 Blast hits to 1766 proteins in 228 species: Archae - 0; Bacteria - 2; Metazoa - 686; Fungi - 563; Plants - 278; Viruses - 0; Other Eukaryotes - 302 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      7353773..7361256
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001036282.2 → NP_001031359.1  transportin 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001031359.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4ILE2, Q8H0U4, Q8H2D6, Q9ZVW8
      UniProtKB/TrEMBL
      A0A178VZY9, A0A5S9WYJ7, A0A654EYI8
      Conserved Domains (2) summary
      COG5215
      Location:16 → 726
      KAP95; Karyopherin (importin) beta [Intracellular trafficking and secretion]
      sd00044
      Location:99 → 120
      HEAT; HEAT repeat [structural motif]

    2. NM_127248.4 → NP_179287.3  transportin 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_179287.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VZY9, A0A5S9WYJ7
      Conserved Domains (4) summary
      pfam03810
      Location:38 → 104
      IBN_N; Importin-beta N-terminal domain
      pfam13513
      Location:411 → 465
      HEAT_EZ; HEAT-like repeat
      pfam13646
      Location:392 → 507
      HEAT_2; HEAT repeats
      sd00044
      Location:395 → 426
      HEAT; HEAT repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8H0U4.1

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