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    basic helix-loop-helix (bHLH) DNA-binding superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 816806, updated on 18-Sep-2024

    Summary

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    Official Full Name
    basic helix-loop-helix (bHLH) DNA-binding superfamily protein
    Primary source
    TAIR:AT2G22760
    Locus tag
    AT2G22760
    See related
    Araport:AT2G22760
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T30L20.2; T30L20_2
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    Genomic context

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    Location:
    chromosome: 2
    Exon count:
    3
    Sequence:
    Chromosome: 2; NC_003071.7 (9677844..9679502)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene SU(VAR)3-9 homolog 6 Neighboring gene basic helix-loop-helix (bHLH) DNA-binding superfamily protein Neighboring gene basic helix-loop-helix (bHLH) DNA-binding superfamily protein Neighboring gene peroxisomal NAD-malate dehydrogenase 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Unequally redundant RCD1 and SRO1 mediate stress and developmental responses and interact with transcription factors. Jaspers P, et al. Plant J, 2009 Oct. PMID 19548978
    2. The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity. Heim MA, et al. Mol Biol Evol, 2003 May. PMID 12679534
    3. Promoter-based integration in plant defense regulation. Li B, et al. Plant Physiol, 2014 Dec. PMID 25352272, Free PMC Article
    4. Regulation of leaf maturation by chromatin-mediated modulation of cytokinin responses. Efroni I, et al. Dev Cell, 2013 Feb 25. PMID 23449474, Free PMC Article
    5. An Arabidopsis gene regulatory network for secondary cell wall synthesis. Taylor-Teeples M, et al. Nature, 2015 Jan 29. PMID 25533953, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001335823.1
    NM_127841.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transcription cis-regulatory region binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of DNA-templated transcription TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    basic helix-loop-helix (bHLH) DNA-binding superfamily protein
    NP_179861.2
    • basic helix-loop-helix (bHLH) DNA-binding superfamily protein; FUNCTIONS IN: DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: regulation of transcription; LOCATED IN: nucleus; EXPRESSED IN: root, cultured cell; CONTAINS InterPro DOMAIN/s: Helix-loop-helix DNA-binding domain (InterPro:IPR001092), Helix-loop-helix DNA-binding (InterPro:IPR011598); BEST Arabidopsis thaliana protein match is: basic helix-loop-helix (bHLH) DNA-binding superfamily protein (TAIR:AT2G22770.1); Has 2563 Blast hits to 2557 proteins in 132 species: Archae - 2; Bacteria - 0; Metazoa - 4; Fungi - 23; Plants - 2520; Viruses - 0; Other Eukaryotes - 14 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      9677844..9679502
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_127841.3 → NP_179861.2  basic helix-loop-helix (bHLH) DNA-binding superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_179861.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0MEP4, O82397, Q1PF16, Q8S3F2
      UniProtKB/TrEMBL
      A0A178VXE3, A0A654F0A7, C0SV56
      Conserved Domains (1) summary
      cd11452
      Location:115 → 189
      bHLH_AtNAI1_like; basic helix-loop-helix (bHLH) domain found in Arabidopsis thaliana protein NAI1 and similar proteins

    2. NM_001335823.1 → NP_001323557.1  basic helix-loop-helix (bHLH) DNA-binding superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VXE3, A0A1P8AXG9
      Conserved Domains (1) summary
      smart00353
      Location:122 → 170
      HLH; helix loop helix domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q1PF16.1

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