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    TRZ1 tRNAse Z1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843809, updated on 18-Sep-2024

    Summary

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    Official Symbol
    TRZ1
    Official Full Name
    tRNAse Z1
    Primary source
    TAIR:AT1G74700
    Locus tag
    AT1G74700
    See related
    Araport:AT1G74700
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F25A4.32; F25A4_32; NUZ; RNASE Z; tRNAse Z1
    Summary
    Encodes a protein with RNAse Z activity suggesting a role in tRNA processing.
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    Genomic context

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    See TRZ1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    8
    Sequence:
    Chromosome: 1; NC_003070.9 (28065014..28067423)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Exostosin family protein Neighboring gene IQ-domain 31 Neighboring gene ADC synthase superfamily protein Neighboring gene C2 calcium/lipid-binding plant phosphoribosyltransferase family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Analysis of the functional modules of the tRNA 3' endonuclease (tRNase Z). Späth B, et al. J Biol Chem, 2005 Oct 21. PMID 16118225
    2. Assigning a function to a conserved group of proteins: the tRNA 3'-processing enzymes. Schiffer S, et al. EMBO J, 2002 Jun 3. PMID 12032089, Free PMC Article
    3. Arabidopsis encodes four tRNase Z enzymes. Canino G, et al. Plant Physiol, 2009 Jul. PMID 19411372, Free PMC Article
    4. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. analysis of tRNase Z conserved motifs and dimers
      Title: Analysis of the functional modules of the tRNA 3' endonuclease (tRNase Z).
    Submit: New GeneRIF Correction

    General gene information

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    NM_106128.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables 3'-tRNA processing endoribonuclease activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within tRNA 3'-end processing IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within tRNA processing TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tRNAse Z1
    NP_177608.2
    • tRNAse Z1 (TRZ1); BEST Arabidopsis thaliana protein match is: Metallo-hydrolase/oxidoreductase superfamily protein (TAIR:AT2G04530.1); Has 2024 Blast hits to 2024 proteins in 946 species: Archae - 244; Bacteria - 1574; Metazoa - 35; Fungi - 17; Plants - 82; Viruses - 0; Other Eukaryotes - 72 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      28065014..28067423
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_106128.3 → NP_177608.2  tRNAse Z1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_177608.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LGU7, Q9CA48, Q9SSF6
      UniProtKB/TrEMBL
      A0A178WQ34, A0A5S9WUD7, Q1WW71
      Conserved Domains (2) summary
      COG1234
      Location:41 → 254
      ElaC; Ribonuclease BN, tRNA processing enzyme [Translation, ribosomal structure and biogenesis]
      cd16272
      Location:17 → 209
      RNaseZ_MBL-fold; Ribonuclease Z; MBL-fold metallo-hydrolase domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8LGU7.3

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