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    ROPGEF2 RHO guanyl-nucleotide exchange factor 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 839250, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ROPGEF2
    Official Full Name
    RHO guanyl-nucleotide exchange factor 2
    Primary source
    TAIR:AT1G01700
    Locus tag
    AT1G01700
    See related
    Araport:AT1G01700
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATROPGEF2; KINASE PARTNER PROTEIN-LIKE; KPP-LIKE; RHO guanyl-nucleotide exchange factor 2; ROP (rho of plants) guanine nucleotide exchange factor 2; T1N6.8; T1N6_8
    Summary
    Encodes a member of KPP-like gene family, homolog of KPP (kinase partner protein) gene in tomato. Also a member of the RopGEF (guanine nucleotide exchange factor) family, containing the novel PRONE domain (plant-specific Rop nucleotide exchanger), which is exclusively active towards members of the Rop subfamily.
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    Genomic context

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    See ROPGEF2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    7
    Sequence:
    Chromosome: 1; NC_003070.9 (259307..261667, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene miscRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene acyl-CoA thioesterase II Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. RopGEF2 is involved in ABA-suppression of seed germination and post-germination growth of Arabidopsis. Zhao S, et al. Plant J, 2015 Dec. PMID 26461226
    2. The RopGEF2-ROP7/ROP2 Pathway Activated by phyB Suppresses Red Light-Induced Stomatal Opening. Wang W, et al. Plant Physiol, 2017 Jun. PMID 28188273, Free PMC Article
    3. ROPGEF1 and ROPGEF4 are functional regulators of ROP11 GTPase in ABA-mediated stomatal closure in Arabidopsis. Li Z, et al. FEBS Lett, 2012 May 7. PMID 22500990
    4. Members of a novel class of Arabidopsis Rho guanine nucleotide exchange factors control Rho GTPase-dependent polar growth. Gu Y, et al. Plant Cell, 2006 Feb. PMID 16415208, Free PMC Article
    5. A new family of RhoGEFs activates the Rop molecular switch in plants. Berken A, et al. Nature, 2005 Aug 25. PMID 15980860

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001331294.1
    NM_001331295.1
    NM_001331296.1
    NM_001331297.1
    NM_100052.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    RHO guanyl-nucleotide exchange factor 2
    NP_171676.1
    • RHO guanyl-nucleotide exchange factor 2 (ROPGEF2); CONTAINS InterPro DOMAIN/s: Rop nucleotide exchanger, PRONE (InterPro:IPR005512); BEST Arabidopsis thaliana protein match is: RHO guanyl-nucleotide exchange factor 3 (TAIR:AT4G00460.2); Has 308 Blast hits to 304 proteins in 16 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 308; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      259307..261667 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_100052.2 → NP_171676.1  RHO guanyl-nucleotide exchange factor 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_171676.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LQ89
      UniProtKB/TrEMBL
      A0A654EAZ1, A0A7G2DR49
      Conserved Domains (1) summary
      pfam03759
      Location:116 → 482
      PRONE; PRONE (Plant-specific Rop nucleotide exchanger)

    2. NM_001331294.1 → NP_001321886.1  RHO guanyl-nucleotide exchange factor 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8ASC5
      Conserved Domains (1) summary
      pfam03759
      Location:116 → 331
      PRONE; PRONE (Plant-specific Rop nucleotide exchanger)

    3. NM_001331295.1 → NP_001321887.1  RHO guanyl-nucleotide exchange factor 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8ASE8, A0A7G2DR49

    4. NM_001331296.1 → NP_001321884.1  RHO guanyl-nucleotide exchange factor 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8ASA3, A0A7G2DR49

    5. NM_001331297.1 → NP_001321885.1  RHO guanyl-nucleotide exchange factor 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8ASC5
      Conserved Domains (1) summary
      pfam03759
      Location:116 → 331
      PRONE; PRONE (Plant-specific Rop nucleotide exchanger)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LQ89.2

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