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    ABCB14 P-glycoprotein 14 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 839694, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ABCB14
    Official Full Name
    P-glycoprotein 14
    Primary source
    TAIR:AT1G28010
    Locus tag
    AT1G28010
    See related
    Araport:AT1G28010
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    Arabidopsis thaliana ATP-binding cassette B14; ATABCB14; ATP-binding cassette B14; F13K9.11; F13K9_11; MDR12; multi-drug resistance 12; P-glycoprotein 14; PGP14
    Summary
    Encodes an ATP-binding cassette (ABC) transporter. Expressed in the vascular tissue of primary stem.
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    Genomic context

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    See ABCB14 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    9
    Sequence:
    Chromosome: 1; NC_003070.9 (9763211..9768113)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein Neighboring gene uncharacterized protein Neighboring gene miscRNA Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The ABC transporter AtABCB14 is a malate importer and modulates stomatal response to CO2. Lee M, et al. Nat Cell Biol, 2008 Oct. PMID 18776898
    2. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_102566.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ABC-type transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATPase-coupled transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    P-glycoprotein 14
    NP_174122.1
    • P-glycoprotein 14 (PGP14); FUNCTIONS IN: ATPase activity, coupled to transmembrane movement of substances; INVOLVED IN: transport, transmembrane transport; LOCATED IN: integral to membrane; EXPRESSED IN: 9 plant structures; EXPRESSED DURING: LP.04 four leaves visible, LP.02 two leaves visible, LP.12 twelve leaves visible; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), ABC transporter, transmembrane domain, type 1 (InterPro:IPR011527), ABC transporter integral membrane type 1 (InterPro:IPR017940), ABC transporter, transmembrane domain (InterPro:IPR001140), ABC transporter, conserved site (InterPro:IPR017871); BEST Arabidopsis thaliana protein match is: P-glycoprotein 13 (TAIR:AT1G27940.1); Has 862231 Blast hits to 397322 proteins in 4187 species: Archae - 14893; Bacteria - 671155; Metazoa - 18443; Fungi - 12341; Plants - 9398; Viruses - 47; Other Eukaryotes - 135954 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      9763211..9768113
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_102566.3 → NP_174122.1  P-glycoprotein 14 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_174122.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9C7F2
      UniProtKB/TrEMBL
      A0A178WF01, A0A5S9W4N4, A0A7G2DW76
      Conserved Domains (1) summary
      PTZ00265
      Location:47 → 1243
      PTZ00265; multidrug resistance protein (mdr1); Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9C7F2.1

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