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    RAV1 uncharacterized protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 837886, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RAV1
    Official Full Name
    uncharacterized protein
    Primary source
    TAIR:AT1G13260
    Locus tag
    AT1G13260
    See related
    Araport:AT1G13260
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtRAV1; EDF4; ETHYLENE RESPONSE DNA BINDING FACTOR 4; related to ABI3/VP1 1; T6J4.2; T6J4_2
    Summary
    Encodes an AP2/B3 domain transcription factor which is upregulated in response to low temperature. It contains a B3 DNA binding domain. It has circadian regulation and may function as a negative growth regulator.
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    Genomic context

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    See RAV1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    1
    Sequence:
    Chromosome: 1; NC_003070.9 (4542168..4543970)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene galacturonosyltransferase-like 3 Neighboring gene ncRNA Neighboring gene methionine aminopeptidase 1B Neighboring gene allene oxide cyclase 4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis RAV1 is down-regulated by brassinosteroid and may act as a negative regulator during plant development. Hu YX, et al. Cell Res, 2004 Feb. PMID 15040885
    2. Solution structure of the B3 DNA binding domain of the Arabidopsis cold-responsive transcription factor RAV1. Yamasaki K, et al. Plant Cell, 2004 Dec. PMID 15548737, Free PMC Article
    3. The RAV1 transcription factor positively regulates leaf senescence in Arabidopsis. Woo HR, et al. J Exp Bot, 2010 Sep. PMID 20826506, Free PMC Article
    4. RAV1, a novel DNA-binding protein, binds to bipartite recognition sequence through two distinct DNA-binding domains uniquely found in higher plants. Kagaya Y, et al. Nucleic Acids Res, 1999 Jan 15. PMID 9862967, Free PMC Article
    5. AtRAV1 and AtRAV2 overexpression in cotton increases fiber length differentially under drought stress and delays flowering. Mittal A, et al. Plant Sci, 2015 Dec. PMID 26706061

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Reciprocal inhibition of expression between RAV1 and BES1 modulates plant growth and development in Arabidopsis.
      Title: Reciprocal inhibition of expression between RAV1 and BES1 modulates plant growth and development in Arabidopsis.
    2. AtRAV1 and AtRAV2-overexpressing cotton had approximately 5% significantly longer fibers with only marginal decreases in yields under well-watered or drought stress conditions that resulted in 40-60% yield penalties and 3-7% fiber length penalties in control plants.
      Title: AtRAV1 and AtRAV2 overexpression in cotton increases fiber length differentially under drought stress and delays flowering.
    3. Data show that FOREVER YOUNG FLOWER UP-REGULATING FACTOR1 (FUF1; At1g71450) acts as an activator in suppressing ETHYLENE RESPONSE DNA BINDING FACTORs EDF1/2/3/4 function and senescence/abscission of the flowers.
      Title: FOREVER YOUNG FLOWER Negatively Regulates Ethylene Response DNA-Binding Factors by Activating an Ethylene-Responsive Factor to Control Arabidopsis Floral Organ Senescence and Abscission.
    4. RAV1 transcription factor plays an important role in abscisic acid signaling by modulating the expression of ABI3, ABI4, and ABI5, and that its activity is negatively affected by SnRK2s.Rav1 is phosphorylated by SnRK2 kinases.
      Title: Arabidopsis RAV1 transcription factor, phosphorylated by SnRK2 kinases, regulates the expression of ABI3, ABI4, and ABI5 during seed germination and early seedling development.
    5. Arabidopsis RAV1, RAV2 and Rav1L transcription factors modulates drought and salt stress responses independent of abscisic acid.
      Title: A subset of Arabidopsis RAV transcription factors modulates drought and salt stress responses independent of ABA.
    6. Transgenic cotton (Gossypium hirsutum) expressing AtRAV1/2 and/or AtABI5 showed resistance to imposed drought stress.
      Title: Related to ABA-Insensitive3(ABI3)/Viviparous1 and AtABI5 transcription factor coexpression in cotton enhances drought stress adaptation.
    7. Results strongly suggest that RAV1 is sufficient to cause leaf senescence and it functions as a positive regulator in this process.
      Title: The RAV1 transcription factor positively regulates leaf senescence in Arabidopsis.
    8. Arabidopsis transcription factors, RAV1 and RAV2, are regulated by touch-related stimuli in a dose-dependent and biphasic manner.
      Title: Arabidopsis transcription factors, RAV1 and RAV2, are regulated by touch-related stimuli in a dose-dependent and biphasic manner.
    9. The RAV1 B3 binding domain consists of a seven-stranded open beta-barrel and two alpha-helices located at the ends of the barrel and is similar to the structure of the noncatalytic DNA binding domain of the restriction enzyme EcoRII.
      Title: Solution structure of the B3 DNA binding domain of the Arabidopsis cold-responsive transcription factor RAV1.
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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_101197.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables transcription cis-regulatory region binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to hypoxia HEP PubMed 
    acts_upstream_of_or_within lateral root development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within leaf development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of flower development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to brassinosteroid IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus HDA PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    NP_172784.1
    • related to ABI3/VP1 1 (RAV1); CONTAINS InterPro DOMAIN/s: DNA-binding, integrase-type (InterPro:IPR016177), Transcriptional factor B3 (InterPro:IPR003340), Pathogenesis-related transcriptional factor/ERF, DNA-binding (InterPro:IPR001471); BEST Arabidopsis thaliana protein match is: ethylene response DNA binding factor 3 (TAIR:AT3G25730.1); Has 6277 Blast hits to 6015 proteins in 258 species: Archae - 0; Bacteria - 3; Metazoa - 0; Fungi - 0; Plants - 6251; Viruses - 0; Other Eukaryotes - 23 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      4542168..4543970
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_101197.4 → NP_172784.1  uncharacterized protein AT1G13260 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_172784.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9ZWM9
      UniProtKB/TrEMBL
      A0A654EAH8
      Conserved Domains (2) summary
      cd00018
      Location:60 → 118
      AP2; DNA-binding domain found in transcription regulators in plants such as APETALA2 and EREBP (ethylene responsive element binding protein). In EREBPs the domain specifically binds to the 11bp GCC box of the ethylene response element (ERE), a promotor ...
      pfam02362
      Location:188 → 292
      B3; B3 DNA binding domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9ZWM9.1

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