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    UBC12 ubiquitin-conjugating enzyme 12 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820017, updated on 18-Sep-2024

    Summary

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    Official Symbol
    UBC12
    Official Full Name
    ubiquitin-conjugating enzyme 12
    Primary source
    TAIR:AT3G08700
    Locus tag
    AT3G08700
    See related
    Araport:AT3G08700
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ubiquitin-conjugating enzyme 12
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    Genomic context

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    See UBC12 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    5
    Sequence:
    Chromosome: 3; NC_003074.8 (2643144..2644775)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Leucine-rich repeat protein kinase family protein Neighboring gene ubiquitin-conjugating enzyme 11 Neighboring gene thioredoxin H-type 9 Neighboring gene serine/threonine protein kinase 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_001337764.1
    NM_111704.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ubiquitin conjugating enzyme activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    ubiquitin-conjugating enzyme 12
    NP_001319500.1
    • ubiquitin-conjugating enzyme 12 (UBC12); FUNCTIONS IN: ubiquitin-protein ligase activity, small conjugating protein ligase activity; INVOLVED IN: regulation of protein metabolic process, post-translational protein modification; LOCATED IN: cellular_component unknown; EXPRESSED IN: 9 plant structures; EXPRESSED DURING: L mature pollen stage, LP.04 four leaves visible, 4 anthesis, LP.10 ten leaves visible, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Ubiquitin-conjugating enzyme/RWD-like (InterPro:IPR016135), Ubiquitin-conjugating enzyme, E2 (InterPro:IPR000608); BEST Arabidopsis thaliana protein match is: ubiquitin-conjugating enzyme 11 (TAIR:AT3G08690.2); Has 10370 Blast hits to 10346 proteins in 401 species: Archae - 0; Bacteria - 2; Metazoa - 4447; Fungi - 2251; Plants - 1964; Viruses - 26; Other Eukaryotes - 1680 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      2643144..2644775
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001337764.1 → NP_001319500.1  ubiquitin-conjugating enzyme 12 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9C9Y7
      UniProtKB/TrEMBL
      A0A654FAJ0

    2. NM_111704.2 → NP_566332.1  ubiquitin-conjugating enzyme 12 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566332.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9C9Y7
      UniProtKB/TrEMBL
      A0A654FAJ0
      Conserved Domains (2) summary
      COG5078
      Location:1 → 148
      COG5078; Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones]
      cl00154
      Location:1 → 147
      UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9C9Y7.1

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