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    AOX1C alternative oxidase 1C [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 822384, updated on 18-Sep-2024

    Summary

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    Official Symbol
    AOX1C
    Official Full Name
    alternative oxidase 1C
    Primary source
    TAIR:AT3G27620
    Locus tag
    AT3G27620
    See related
    Araport:AT3G27620
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    alternative oxidase 1C
    Summary
    encodes an isoform of alternate oxidase. expressed in all tissues examined and expression is not induced by antimycin A, an inhibitor of complex III in the mitochondrial respiratory chain.
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    Genomic context

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    See AOX1C in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    4
    Sequence:
    Chromosome: 3; NC_003074.8 (10229045..10230707, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene SWAP (Suppressor-of-White-APricot)/surp RNA-binding domain-containing protein Neighboring gene Nucleotidylyl transferase superfamily protein Neighboring gene cyclin-dependent kinase inhibitor SMR3-like protein Neighboring gene Transducin/WD40 repeat-like superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of the gene family for alternative oxidase from Arabidopsis thaliana. Saisho D, et al. Plant Mol Biol, 1997 Nov. PMID 9349280
    2. Alternative Oxidase Isoforms Are Differentially Activated by Tricarboxylic Acid Cycle Intermediates. Selinski J, et al. Plant Physiol, 2018 Feb. PMID 29208641, Free PMC Article
    3. Analysis of Posttranslational Activation of Alternative Oxidase Isoforms. Selinski J, et al. Plant Physiol, 2017 Aug. PMID 28596420, Free PMC Article
    4. Functional Relationship of Arabidopsis AOXs and PTOX Revealed via Transgenic Analysis. Wang D, et al. Front Plant Sci, 2021. PMID 34367216, Free PMC Article
    5. Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins. Heazlewood JL, et al. Plant Cell, 2004 Jan. PMID 14671022, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. AOX1C activation by Tricarboxylic acid cycle Intermediates.
      Title: Alternative Oxidase Isoforms Are Differentially Activated by Tricarboxylic Acid Cycle Intermediates.
    2. AOX isoforms are differentially activated and that activation at CysI and CysII is additive.
      Title: Analysis of Posttranslational Activation of Alternative Oxidase Isoforms.
    Submit: New GeneRIF Correction

    General gene information

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    NM_113678.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables alternative oxidase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables superoxide-generating NADPH oxidase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables ubiquinol:oxygen oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    alternative oxidase 1C
    NP_189399.1
    • alternative oxidase 1C (AOX1C); CONTAINS InterPro DOMAIN/s: Alternative oxidase (InterPro:IPR002680); BEST Arabidopsis thaliana protein match is: alternative oxidase 1B (TAIR:AT3G22360.1); Has 1310 Blast hits to 1304 proteins in 245 species: Archae - 0; Bacteria - 111; Metazoa - 12; Fungi - 192; Plants - 384; Viruses - 0; Other Eukaryotes - 611 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      10229045..10230707 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_113678.3 → NP_189399.1  alternative oxidase 1C [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_189399.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O22048
      UniProtKB/TrEMBL
      A0A654FBA7, A0A7G2ETS7
      Conserved Domains (1) summary
      PLN02478
      Location:5 → 329
      PLN02478; alternative oxidase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O22048.1

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