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    ATE2 arginine-tRNA protein transferase 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820295, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ATE2
    Official Full Name
    arginine-tRNA protein transferase 2
    Primary source
    TAIR:AT3G11240
    Locus tag
    AT3G11240
    See related
    Araport:AT3G11240
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    arginine-tRNA protein transferase 2; ATATE2
    Summary
    Encodes an arginyl-tRNA:protein arginyltransferase (ATE2), a component of the N-end rule pathway that targets protein degradation through the identity of the amino-terminal residue of specific protein substrates. Arabidopsis contains two ATE genes: At5g05700/ATE1, At3g11240/ATE2. Another component of the N-end rule pathway is At5g02310/PROTEOLYSIS6 (PRT6). PRT6 and ATE were shown to regulate seed after-ripening, seedling sugar sensitivity, seedling lipid breakdown, and abscisic acid (ABA) sensitivity of germination.
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    Genomic context

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    See ATE2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    4
    Sequence:
    Chromosome: 3; NC_003074.8 (3518472..3521188, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene alfin-like 2 Neighboring gene SGNH hydrolase-type esterase superfamily protein Neighboring gene Paxneb protein-like protein Neighboring gene Yippee family putative zinc-binding protein Neighboring gene Ribosomal protein L10 family protein Neighboring gene WUSCHEL related homeobox 5

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The N-end rule pathway regulates pathogen responses in plants. de Marchi R, et al. Sci Rep, 2016 May 13. PMID 27173012, Free PMC Article
    2. The N-end rule pathway promotes seed germination and establishment through removal of ABA sensitivity in Arabidopsis. Holman TJ, et al. Proc Natl Acad Sci U S A, 2009 Mar 17. PMID 19255443, Free PMC Article
    3. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_001337920.1
    NM_001337921.1
    NM_001337922.1
    NM_111959.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables arginyl-tRNA--protein transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within defense response to fungus IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of lipid catabolic process IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of seed germination IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within response to abscisic acid IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    arginine-tRNA protein transferase 2
    NP_187733.1
    • arginine-tRNA protein transferase 2 (ATE2); FUNCTIONS IN: arginyltransferase activity; INVOLVED IN: regulation of seed germination, regulation of lipid catabolic process, protein arginylation, response to abscisic acid stimulus; LOCATED IN: cellular_component unknown; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: Arginine-tRNA-protein transferase, N-terminal (InterPro:IPR007471), Arginine-tRNA-protein transferase 1, eukaryotic (InterPro:IPR017137), Arginine-tRNA-protein transferase, C-terminal (InterPro:IPR007472); BEST Arabidopsis thaliana protein match is: arginine-tRNA protein transferase 1 (TAIR:AT5G05700.1); Has 2270 Blast hits to 2031 proteins in 783 species: Archae - 0; Bacteria - 1438; Metazoa - 213; Fungi - 241; Plants - 48; Viruses - 0; Other Eukaryotes - 330 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      3518472..3521188 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001337919.1 → NP_001326206.1  arginine-tRNA protein transferase 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LNK5

    2. NM_111959.3 → NP_187733.1  arginine-tRNA protein transferase 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_187733.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9C776
      UniProtKB/TrEMBL
      A0A5S9XCE8
      Conserved Domains (3) summary
      smart01016
      Location:161 → 273
      Arg_tRNA_synt_N; Arginyl tRNA synthetase N terminal dom
      pfam04376
      Location:32 → 105
      ATE_N; Arginine-tRNA-protein transferase, N terminus
      pfam04377
      Location:322 → 468
      ATE_C; Arginine-tRNA-protein transferase, C terminus

    3. NM_001337921.1 → NP_001326208.1  arginine-tRNA protein transferase 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LNK5

    4. NM_001337920.1 → NP_001326207.1  arginine-tRNA protein transferase 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LNK3, A0A5S9XCE8

    5. NM_001337922.1 → NP_001326209.1  arginine-tRNA protein transferase 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LNK5
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9C776.1

    Gene LinkOut

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