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    disease resistance protein (TIR-NBS-LRR class) [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 829771, updated on 18-Sep-2024

    Summary

    Official Full Name
    disease resistance protein (TIR-NBS-LRR class)
    Primary source
    TAIR:AT4G36140
    Locus tag
    AT4G36140
    See related
    Araport:AT4G36140
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F23E13.30; F23E13_30
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    Genomic context

    Location:
    chromosome: 4
    Exon count:
    7
    Sequence:
    Chromosome: 4; NC_003075.7 (17098612..17104576, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene SAUR-like auxin-responsive protein family Neighboring gene filament-like protein (DUF869) Neighboring gene Ribosomal protein L2 family Neighboring gene Disease resistance protein (TIR-NBS-LRR class) family Neighboring gene NAC domain containing protein 76 Neighboring gene uncharacterized protein Neighboring gene Leucine-rich receptor-like protein kinase family protein

    General gene information

    Markers

    NM_001342405.1
    NM_119781.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ADP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
     
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
     

    General protein information

    Preferred Names
    disease resistance protein (TIR-NBS-LRR class)
    NP_195337.1
    • disease resistance protein (TIR-NBS-LRR class), putative; FUNCTIONS IN: transmembrane receptor activity, nucleoside-triphosphatase activity, nucleotide binding, ATP binding; INVOLVED IN: signal transduction, defense response, apoptosis, innate immune response; LOCATED IN: intrinsic to membrane; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), NB-ARC (InterPro:IPR002182), Toll-Interleukin receptor (InterPro:IPR000157), Disease resistance protein (InterPro:IPR000767); BEST Arabidopsis thaliana protein match is: Disease resistance protein (TIR-NBS-LRR class) (TAIR:AT5G45050.1); Has 19842 Blast hits to 11670 proteins in 467 species: Archae - 4; Bacteria - 629; Metazoa - 268; Fungi - 32; Plants - 18688; Viruses - 0; Other Eukaryotes - 221 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      17098612..17104576 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_119781.2NP_195337.1  disease resistance protein (TIR-NBS-LRR class) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_195337.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654FVY5, O65506
      Conserved Domains (6) summary
      PLN03210
      Location:4491269
      PLN03210; Resistant to P. syringae 6; Provisional
      sd00033
      Location:10111033
      LRR_RI; leucine-rich repeat [structural motif]
      pfam01582
      Location:50259
      TIR; TIR domain
      pfam07725
      Location:10101029
      LRR_3; Leucine Rich Repeat
      pfam13191
      Location:607716
      AAA_16; AAA ATPase domain
      pfam13207
      Location:291325
      AAA_17; AAA domain
    2. NM_001342405.1NP_001329411.1  disease resistance protein (TIR-NBS-LRR class) [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B7M2, A0A654FVY5