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    pyruvate kinase family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 824077, updated on 18-Sep-2024

    Summary

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    Official Full Name
    pyruvate kinase family protein
    Primary source
    TAIR:AT3G49160
    Locus tag
    AT3G49160
    See related
    Araport:AT3G49160
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Summary
    Expression of the gene is downregulated in the presence of paraquat, an inducer of photoxidative stress.
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    Genomic context

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    Location:
    chromosome: 3
    Exon count:
    4
    Sequence:
    Chromosome: 3; NC_003074.8 (18221794..18224905, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene F-box/FBD/LRR protein Neighboring gene F-box/LRR protein Neighboring gene miscRNA Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    2. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001339401.1
    NM_001339402.1
    NM_114775.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables potassium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables pyruvate kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in glycolytic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    pyruvate kinase family protein
    NP_190485.1
    • pyruvate kinase family protein; FUNCTIONS IN: pyruvate kinase activity, magnesium ion binding, potassium ion binding, catalytic activity; INVOLVED IN: glycolysis; LOCATED IN: cellular_component unknown; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Pyruvate/Phosphoenolpyruvate kinase, catalytic core (InterPro:IPR015813), Pyruvate kinase, beta-barrel-like (InterPro:IPR011037), Pyruvate kinase (InterPro:IPR001697), Pyruvate kinase, barrel (InterPro:IPR015793); BEST Arabidopsis thaliana protein match is: Pyruvate kinase family protein (TAIR:AT5G63680.1); Has 14581 Blast hits to 9515 proteins in 2692 species: Archae - 258; Bacteria - 9751; Metazoa - 816; Fungi - 346; Plants - 707; Viruses - 0; Other Eukaryotes - 2703 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      18221794..18224905 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_114775.3 → NP_190485.1  pyruvate kinase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_190485.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9M3B6
      UniProtKB/TrEMBL
      A0A178V7E0
      Conserved Domains (2) summary
      PRK08187
      Location:106 → 695
      PRK08187; pyruvate kinase; Validated
      cl23794
      Location:94 → 695
      Pyruvate_Kinase; Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low ...

    2. NM_001339401.1 → NP_001325915.1  pyruvate kinase family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LMN8

    3. NM_001339402.1 → NP_001325914.1  pyruvate kinase family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LMN7, A0A654FFI0
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9M3B6.1

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