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    MSL2 MSCS-like 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 830913, updated on 23-Sep-2024

    Summary

    Official Symbol
    MSL2
    Official Full Name
    MSCS-like 2
    Primary source
    TAIR:AT5G10490
    Locus tag
    AT5G10490
    See related
    Araport:AT5G10490
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F12B17.160; F12B17_160; MSCS-like 2
    Summary
    A member of MscS-like gene family, structurally very similar to MSL3, comprising of an N-terminal chloroplast transit peptide, five trans-membrane helices and a C-terminal cytoplasmic domain. Mutant plants showed abnormalities in the size and shape of plastids. MSL2-GFP was localized to discrete foci on the plastid envelope and co-localize with the plastid division protein AtMinE.
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    Genomic context

    See MSL2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    14
    Sequence:
    Chromosome: 5; NC_003076.8 (3300192..3304784, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Haloacid dehalogenase-like hydrolase (HAD) superfamily protein Neighboring gene kinesin like protein for actin based chloroplast movement 1 Neighboring gene Protein-tyrosine phosphatase-like, PTPLA Neighboring gene Kinase interacting (KIP1-like) family protein Neighboring gene ncRNA

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    General gene information

    NM_001203349.1
    NM_121087.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables monoatomic ion channel activity IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within chloroplast fission IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within plastid organization IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
     
    located_in plastid envelope IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    MSCS-like 2
    NP_001078567.1
    • MSCS-like 2 (MSL2); FUNCTIONS IN: ion channel activity; INVOLVED IN: plastid organization; LOCATED IN: chloroplast, membrane, plastid envelope; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Mechanosensitive ion channel MscS (InterPro:IPR006685), Like-Sm ribonucleoprotein (LSM)-related domain (InterPro:IPR010920); BEST Arabidopsis thaliana protein match is: MSCS-like 3 (TAIR:AT1G58200.2); Has 4285 Blast hits to 4245 proteins in 1032 species: Archae - 175; Bacteria - 2256; Metazoa - 237; Fungi - 57; Plants - 186; Viruses - 3; Other Eukaryotes - 1371 (source: NCBI BLink).
    NP_001190278.1
    • MSCS-like 2 (MSL2); CONTAINS InterPro DOMAIN/s: Like-Sm ribonucleoprotein (LSM)-related domain (InterPro:IPR010920), Mechanosensitive ion channel MscS (InterPro:IPR006685); BEST Arabidopsis thaliana protein match is: MSCS-like 3 (TAIR:AT1G58200.2).
    NP_568230.2
    • MSCS-like 2 (MSL2); FUNCTIONS IN: ion channel activity; INVOLVED IN: plastid organization; LOCATED IN: chloroplast, membrane, plastid envelope; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Mechanosensitive ion channel MscS (InterPro:IPR006685), Like-Sm ribonucleoprotein (LSM)-related domain (InterPro:IPR010920); BEST Arabidopsis thaliana protein match is: MSCS-like 3 (TAIR:AT1G58200.2); Has 4292 Blast hits to 4247 proteins in 1034 species: Archae - 175; Bacteria - 2259; Metazoa - 236; Fungi - 59; Plants - 186; Viruses - 3; Other Eukaryotes - 1374 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      3300192..3304784 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001085098.2NP_001078567.1  MSCS-like 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001078567.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9Y3L1
      Conserved Domains (2) summary
      COG0668
      Location:131448
      MscS; Small-conductance mechanosensitive channel [Cell wall/membrane/envelope biogenesis]
      pfam00924
      Location:216408
      MS_channel; Mechanosensitive ion channel
    2. NM_121087.3NP_568230.2  MSCS-like 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568230.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B9DHF7, F4KGW2, Q56X46, Q9LXA1
      UniProtKB/TrEMBL
      A0A5S9Y3L1
      Conserved Domains (2) summary
      COG0668
      Location:159476
      MscS; Small-conductance mechanosensitive channel [Cell wall/membrane/envelope biogenesis]
      pfam00924
      Location:244436
      MS_channel; Mechanosensitive ion channel
    3. NM_001203349.1NP_001190278.1  MSCS-like 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190278.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9Y3L1
      Conserved Domains (2) summary
      COG0668
      Location:157474
      MscS; Small-conductance mechanosensitive channel [Cell wall/membrane/envelope biogenesis]
      pfam00924
      Location:242434
      MS_channel; Mechanosensitive ion channel