SCP2 sterol carrier protein 2 [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: SCP2
Official Full Name: sterol carrier protein 2
Primary source: TAIR:AT5G42890
Locus tag: AT5G42890
See related: Araport:AT5G42890
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ATSCP2; MBD2.8; MBD2_8; sterol carrier protein 2; STEROL CARRIER PROTEIN 2
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Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

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AtSCP2 is important for the metabolism in A. thaliana seeds and seedlings.
Title: Arabidopsis sterol carrier protein-2 is required for normal development of seeds and seedlings.
analysis of SCP-2 from Arabidopsis
Title: Plants express a lipid transfer protein with high similarity to mammalian sterol carrier protein-2.
Arabidopsis SCP-2 is localised to peroxisomes and showed in vitro transfer activity of BODIPY-phosphatidylcholine (BODIPY-PC) from donor membranes to acceptor membranes.
Title: Plants express a lipid transfer protein with high similarity to mammalian sterol carrier protein-2.

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NM_123654.4

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within fatty acid beta-oxidation	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within glyoxylate metabolic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in intracellular lipid transport	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within intracellular lipid transport	TAS Traceable Author Statement more info	PubMed
involved_in response to absence of light	IEP Inferred from Expression Pattern more info	PubMed
involved_in response to sucrose	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within seed germination	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in seed morphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in chloroplast	ISM Inferred from Sequence Model more info
located_in peroxisome	HDA more info	PubMed
located_in peroxisome	IDA Inferred from Direct Assay more info	PubMed

NP_199103.1

sterol carrier protein 2 (SCP2); FUNCTIONS IN: oxidoreductase activity, sterol binding; INVOLVED IN: glyoxylate metabolic process, intracellular lipid transport, fatty acid beta-oxidation, seed germination; LOCATED IN: peroxisome; EXPRESSED IN: 32 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: SCP2 sterol-binding domain (InterPro:IPR003033), Short-chain dehydrogenase/reductase SDR (InterPro:IPR002198); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

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