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    ATBCAT-5 branched-chain amino acid aminotransferase 5 / branched-chain amino acid transaminase 5 (BCAT5) [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 836707, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ATBCAT-5
    Official Full Name
    branched-chain amino acid aminotransferase 5 / branched-chain amino acid transaminase 5 (BCAT5)
    Primary source
    TAIR:AT5G65780
    Locus tag
    AT5G65780
    See related
    Araport:AT5G65780
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MPA24.13; MPA24_13
    Summary
    Encodes a chloroplast branched-chain amino acid aminotransferase, can complement the yeast leu/iso-leu/val auxotrophy mutant. Note that the AT5G65780.2 gene model (TAIR10) has been obsoleted due to the lack of experimental support.
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    Genomic context

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    See ATBCAT-5 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    12
    Sequence:
    Chromosome: 5; NC_003076.8 (26311311..26318857)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene zinc ion binding protein Neighboring gene 2-oxoglutarate dehydrogenase, E1 component Neighboring gene Serine carboxypeptidase S28 family protein Neighboring gene branched-chain amino acid aminotransferase 5 / branched-chain amino acid transaminase 5 (BCAT5);little nuclei4 Neighboring gene myb domain protein 68 Neighboring gene ACC synthase 5

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The branched-chain amino acid transaminase gene family in Arabidopsis encodes plastid and mitochondrial proteins. Diebold R, et al. Plant Physiol, 2002 Jun. PMID 12068099, Free PMC Article
    2. Lipoic acid-dependent oxidative catabolism of alpha-keto acids in mitochondria provides evidence for branched-chain amino acid catabolism in Arabidopsis. Taylor NL, et al. Plant Physiol, 2004 Feb. PMID 14764908, Free PMC Article
    3. Arabidopsis G-protein interactome reveals connections to cell wall carbohydrates and morphogenesis. Klopffleisch K, et al. Mol Syst Biol, 2011 Sep 27. PMID 21952135, Free PMC Article
    4. Sorting signals, N-terminal modifications and abundance of the chloroplast proteome. Zybailov B, et al. PLoS One, 2008 Apr 23. PMID 18431481, Free PMC Article
    5. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_125975.8

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables L-isoleucine-2-oxoglutarate transaminase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables L-leucine-2-oxoglutarate transaminase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables L-valine-2-oxoglutarate transaminase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables branched-chain-amino-acid transaminase activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in L-leucine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in L-valine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in isoleucine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in nucleus organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    branched-chain amino acid aminotransferase 5 / branched-chain amino acid transaminase 5 (BCAT5)
    NP_201379.2
    • ATBCAT-5; FUNCTIONS IN: branched-chain-amino-acid transaminase activity, catalytic activity; INVOLVED IN: branched chain family amino acid metabolic process, metabolic process; LOCATED IN: mitochondrion, chloroplast; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Aminotransferase, class IV (InterPro:IPR001544), Aminotransferase, class IV, conserved site (InterPro:IPR018300), Branched-chain amino acid aminotransferase II (InterPro:IPR005786); BEST Arabidopsis thaliana protein match is: branched-chain aminotransferase 3 (TAIR:AT3G49680.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      26311311..26318857
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_125975.8 → NP_201379.2  branched-chain amino acid aminotransferase 5 / branched-chain amino acid transaminase 5 (BCAT5) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_201379.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O49539, Q9FLG9, Q9FYA6
      UniProtKB/TrEMBL
      A0A178UDR9, A0A384KYR5, Q0V7U6, Q0WQT2
      Conserved Domains (1) summary
      PLN02782
      Location:13 → 415
      PLN02782; Branched-chain amino acid aminotransferase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FYA6.1

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