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    HDA2 histone deacetylase 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 832673, updated on 18-Sep-2024

    Summary

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    Official Symbol
    HDA2
    Official Full Name
    histone deacetylase 2
    Primary source
    TAIR:AT5G26040
    Locus tag
    AT5G26040
    See related
    Araport:AT5G26040
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    HISTONE DEACETYLASE; histone deacetylase 2; T1N24.9; T1N24_9
    Summary
    Class III RPD3 type protein. Encodes HDA2, a member of the histone deacetylase family proteins.
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    Genomic context

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    See HDA2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    12
    Sequence:
    Chromosome: 5; NC_003076.8 (9099152..9101682, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene ferrochelatase 1 Neighboring gene ncRNA Neighboring gene Plant self-incompatibility protein S1 family Neighboring gene Plant self-incompatibility protein S1 family

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structure of Arabidopsis HISTONE DEACETYLASE15. Chen CY, et al. Plant Physiol, 2020 Nov. PMID 32878973, Free PMC Article
    2. Analysis of histone acetyltransferase and histone deacetylase families of Arabidopsis thaliana suggests functional diversification of chromatin modification among multicellular eukaryotes. Pandey R, et al. Nucleic Acids Res, 2002 Dec 1. PMID 12466527, Free PMC Article
    3. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_122505.4
    NM_180747.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables histone deacetylase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables histone deacetylase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables zinc ion binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    histone deacetylase 2
    NP_568480.2
    • histone deacetylase 2 (HDA2); CONTAINS InterPro DOMAIN/s: Histone deacetylase superfamily (InterPro:IPR000286); BEST Arabidopsis thaliana protein match is: histone deacetylase 6 (TAIR:AT5G63110.1); Has 8459 Blast hits to 8281 proteins in 1419 species: Archae - 213; Bacteria - 3093; Metazoa - 1435; Fungi - 484; Plants - 429; Viruses - 0; Other Eukaryotes - 2805 (source: NCBI BLink).
    NP_851078.1
    • histone deacetylase 2 (HDA2); CONTAINS InterPro DOMAIN/s: Histone deacetylase superfamily (InterPro:IPR000286); BEST Arabidopsis thaliana protein match is: histone deacetylase 9 (TAIR:AT3G44680.1); Has 5195 Blast hits to 5176 proteins in 1086 species: Archae - 142; Bacteria - 1739; Metazoa - 784; Fungi - 275; Plants - 317; Viruses - 0; Other Eukaryotes - 1938 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      9099152..9101682 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_122505.4 → NP_568480.2  histone deacetylase 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568480.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q3E940, Q8LRK7, Q944K3, Q9XH00
      UniProtKB/TrEMBL
      A0A178UN60, A0A5S9Y797, A0A654G4H5
      Conserved Domains (1) summary
      cd09993
      Location:93 → 376
      HDAC_classIV; Histone deacetylase class IV also known as histone deacetylase 11

    2. NM_180747.2 → NP_851078.1  histone deacetylase 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_851078.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9Y797, A0A654G4H5
      Conserved Domains (1) summary
      cd09993
      Location:93 → 348
      HDAC_classIV; Histone deacetylase class IV also known as histone deacetylase 11
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q944K3.2

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