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    Major facilitator superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831564, updated on 18-Sep-2024

    Summary

    Official Full Name
    Major facilitator superfamily protein
    Primary source
    TAIR:AT5G17010
    Locus tag
    AT5G17010
    See related
    Araport:AT5G17010
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F2K13.160; F2K13_160
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    Genomic context

    Location:
    chromosome: 5
    Exon count:
    14
    Sequence:
    Chromosome: 5; NC_003076.8 (5587344..5592534, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Zinc-binding dehydrogenase family protein Neighboring gene Zinc-binding dehydrogenase family protein Neighboring gene exportin 1A Neighboring gene UDP-glucosyl transferase 78D3

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    NM_001343477.1
    NM_121707.3
    NM_180504.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables carbohydrate transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
     
    located_in plant-type vacuole HDA PubMed 
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
     
    located_in plastid HDA PubMed 

    General protein information

    Preferred Names
    Major facilitator superfamily protein
    NP_001318578.1
    • Major facilitator superfamily protein; FUNCTIONS IN: carbohydrate transmembrane transporter activity, sugar:hydrogen symporter activity; INVOLVED IN: transport, transmembrane transport; LOCATED IN: membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Sugar transporter, conserved site (InterPro:IPR005829), Major facilitator superfamily (InterPro:IPR020846), General substrate transporter (InterPro:IPR005828), Sugar/inositol transporter (InterPro:IPR003663), Major facilitator superfamily, general substrate transporter (InterPro:IPR016196); BEST Arabidopsis thaliana protein match is: vacuolar glucose transporter 1 (TAIR:AT3G03090.1).
    NP_197203.1
    • Major facilitator superfamily protein; FUNCTIONS IN: carbohydrate transmembrane transporter activity, sugar:hydrogen symporter activity; INVOLVED IN: transport, transmembrane transport; LOCATED IN: plasma membrane, membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Sugar transporter, conserved site (InterPro:IPR005829), Major facilitator superfamily (InterPro:IPR020846), General substrate transporter (InterPro:IPR005828), Sugar/inositol transporter (InterPro:IPR003663), Major facilitator superfamily, general substrate transporter (InterPro:IPR016196); BEST Arabidopsis thaliana protein match is: vacuolar glucose transporter 1 (TAIR:AT3G03090.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
    NP_850835.2
    • Major facilitator superfamily protein; FUNCTIONS IN: carbohydrate transmembrane transporter activity, sugar:hydrogen symporter activity; INVOLVED IN: transport, transmembrane transport; LOCATED IN: plasma membrane, membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Sugar transporter, conserved site (InterPro:IPR005829), Major facilitator superfamily (InterPro:IPR020846), Sugar/inositol transporter (InterPro:IPR003663), General substrate transporter (InterPro:IPR005828), Major facilitator superfamily, general substrate transporter (InterPro:IPR016196); BEST Arabidopsis thaliana protein match is: vacuolar glucose transporter 1 (TAIR:AT3G03090.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_850836.2
    • Major facilitator superfamily protein; FUNCTIONS IN: carbohydrate transmembrane transporter activity, sugar:hydrogen symporter activity; INVOLVED IN: transport, transmembrane transport; LOCATED IN: plasma membrane, membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Sugar transporter, conserved site (InterPro:IPR005829), Major facilitator superfamily (InterPro:IPR020846), General substrate transporter (InterPro:IPR005828), Sugar/inositol transporter (InterPro:IPR003663), Major facilitator superfamily, general substrate transporter (InterPro:IPR016196); BEST Arabidopsis thaliana protein match is: vacuolar glucose transporter 1 (TAIR:AT3G03090.1); Has 52652 Blast hits to 52024 proteins in 2605 species: Archae - 922; Bacteria - 34397; Metazoa - 4710; Fungi - 7986; Plants - 2480; Viruses - 2; Other Eukaryotes - 2155 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      5587344..5592534 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_180505.3NP_850836.2  Major facilitator superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850836.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4KFK8, Q6AWX0, Q9LFK1
      UniProtKB/TrEMBL
      A0A178UGZ3, A0A5S9Y748
      Conserved Domains (1) summary
      cd17362
      Location:53498
      MFS_GLUT10_12_Class3_like; Glucose transporter (GLUT) types 10 and 12, Class 3 GLUTs, and similar transporters of the Major Facilitator Superfamily
    2. NM_001343477.1NP_001318578.1  Major facilitator superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4KFK8, Q6AWX0, Q9LFK1
      UniProtKB/TrEMBL
      A0A178UGZ3, A0A5S9Y748
      Conserved Domains (1) summary
      cd17362
      Location:53498
      MFS_GLUT10_12_Class3_like; Glucose transporter (GLUT) types 10 and 12, Class 3 GLUTs, and similar transporters of the Major Facilitator Superfamily
    3. NM_180504.3NP_850835.2  Major facilitator superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850835.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4KFK8, Q6AWX0, Q9LFK1
      UniProtKB/TrEMBL
      A0A178UGZ3, A0A5S9Y748
      Conserved Domains (1) summary
      cd17362
      Location:53498
      MFS_GLUT10_12_Class3_like; Glucose transporter (GLUT) types 10 and 12, Class 3 GLUTs, and similar transporters of the Major Facilitator Superfamily
    4. NM_121707.3NP_197203.1  Major facilitator superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_197203.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9Y748, F4KFK7
      Conserved Domains (2) summary
      cd06174
      Location:95424
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      pfam00083
      Location:49436
      Sugar_tr; Sugar (and other) transporter