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    CLPB2 casein lytic proteinase B2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 827117, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CLPB2
    Official Full Name
    casein lytic proteinase B2
    Primary source
    TAIR:AT4G14670
    Locus tag
    AT4G14670
    See related
    Araport:AT4G14670
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    casein lytic proteinase B2; DL3375W; FCAALL.285
    Summary
    This locus was originally annotated as encoding ClpB2 (also referred to as Hsp92.7), which belongs to the Casein lytic proteinase/heat shock protein 100 (Clp/Hsp100) family. However, according to Lee et al. (2007, Plant Journal, 49:115-127), there is no evidence for expression of an appropriate-sized mRNA from this locus. Re-annotation of the genome indicates that this locus potentially encodes a 68.8-kDa protein, containing only the N-terminal two thirds of the originally predicted open reading frame. This locus contains a 626-bp deletion in WS ecotype compared with the Col ecotype, which eliminates residues 1-86 of the predicted protein.
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    Genomic context

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    See CLPB2 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    5
    Sequence:
    Chromosome: 4; NC_003075.7 (8410054..8412557)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene RNA polymerase Rpb7-like, N-terminal domain-containing protein Neighboring gene miscRNA Neighboring gene chaperone ClpB1-like protein Neighboring gene Pseudouridine synthase/archaeosine transglycosylase-like family protein Neighboring gene Chlorophyll A-B binding family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A high- and low-temperature inducible Arabidopsis thaliana HSP101 promoter located in a nonautonomous mutator-like element. Young LW, et al. Genome, 2005 Jun. PMID 16121251
    2. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article
    3. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    casein lytic proteinase B2
    NP_567437.1
    • casein lytic proteinase B2 (CLPB2); FUNCTIONS IN: nucleoside-triphosphatase activity, nucleotide binding, ATP binding; INVOLVED IN: protein metabolic process; LOCATED IN: cellular_component unknown; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ATPase, AAA-2 (InterPro:IPR013093), ATPase, AAA-type, core (InterPro:IPR003959), Chaperonin clpA/B (InterPro:IPR001270), Clp, N-terminal (InterPro:IPR004176); BEST Arabidopsis thaliana protein match is: heat shock protein 101 (TAIR:AT1G74310.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      8410054..8412557
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      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_117549.1 → NP_567437.1  casein lytic proteinase B2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_567437.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4JVJ1, O23323
      UniProtKB/TrEMBL
      A0A5S9XU61
      Conserved Domains (5) summary
      cd00009
      Location:147 → 307
      AAA; The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, ...
      smart00382
      Location:164 → 307
      AAA; ATPases associated with a variety of cellular activities
      pfam02861
      Location:77 → 122
      Clp_N; Clp amino terminal domain, pathogenicity island component
      pfam07724
      Location:565 → 620
      AAA_2; AAA domain (Cdc48 subfamily)
      cl21455
      Location:536 → 584
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    F4JVJ1.1

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