U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Plant invertase/pectin methylesterase inhibitor superfamily [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 819130, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Full Name
    Plant invertase/pectin methylesterase inhibitor superfamily
    Primary source
    TAIR:AT2G45220
    Locus tag
    AT2G45220
    See related
    Araport:AT2G45220
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtPME17; F4L23.27; pectin methylesterase 17; PME17
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Location:
    chromosome: 2
    Exon count:
    2
    Sequence:
    Chromosome: 2; NC_003071.7 (18644061..18646606, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene golgi snare 12 Neighboring gene SAUR-like auxin-responsive protein family Neighboring gene pseudo Neighboring gene methionine aminopeptidase 1A

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. AtPME17 is a functional Arabidopsis thaliana pectin methylesterase regulated by its PRO region that triggers PME activity in the resistance to Botrytis cinerea. Del Corpo D, et al. Mol Plant Pathol, 2020 Dec. PMID 33029918, Free PMC Article
    2. Arabidopsis PME17 Activity can be Controlled by Pectin Methylesterase Inhibitor4. Sénéchal F, et al. Plant Signal Behav, 2015. PMID 25826258, Free PMC Article
    3. Arabidopsis PECTIN METHYLESTERASE17 is co-expressed with and processed by SBT3.5, a subtilisin-like serine protease. Sénéchal F, et al. Ann Bot, 2014 Oct. PMID 24665109, Free PMC Article
    4. Arabidopsis subtilases promote defense-related pectin methylesterase activity and robust immune responses to botrytis infection. Coculo D, et al. Plant Physiol Biochem, 2023 Aug. PMID 37467533
    5. Structural and dynamical characterization of the pH-dependence of the pectin methylesterase-pectin methylesterase inhibitor complex. Sénéchal F, et al. J Biol Chem, 2017 Dec 29. PMID 29109147, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. AtPME17 is a functional Arabidopsis thaliana pectin methylesterase regulated by its PRO region that triggers PME activity in the resistance to Botrytis cinerea.
      Title: AtPME17 is a functional Arabidopsis thaliana pectin methylesterase regulated by its PRO region that triggers PME activity in the resistance to Botrytis cinerea.
    2. Analysis of the ability of Glu-68AtPMEI7 and Glu-75AtPMEI7 to establish hydrogen bonds with AtPME3 revealed that these residues may play an important role in defining complex stability and formation.
      Title: Structural and dynamical characterization of the pH-dependence of the pectin methylesterase-pectin methylesterase inhibitor complex.
    3. PMEI4, is co-expressed with PME17 and is likely to regulate its activity. possible interplay of specific PMEs, PMEIs and SBTs in the fine-tuning of pectin structure.[PME17]
      Title: Arabidopsis PME17 Activity can be Controlled by Pectin Methylesterase Inhibitor4.
    4. AtPME17 (At2g45220), was highly co-expressed, both spatially and temporally, with AtSBT3.5 (At1g32940) during root development. AtSBT3.5 play a role in the processing of AtPME17 in planta.
      Title: Arabidopsis PECTIN METHYLESTERASE17 is co-expressed with and processed by SBT3.5, a subtilisin-like serine protease.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help
    NM_130085.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables enzyme inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables pectinesterase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell wall modification IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within defense response to Gram-negative bacterium IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in pectin catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within response to bacterium IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to fungus IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in apoplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasmic stress granule IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Plant invertase/pectin methylesterase inhibitor superfamily
    NP_566038.1
    • Plant invertase/pectin methylesterase inhibitor superfamily; FUNCTIONS IN: enzyme inhibitor activity, pectinesterase activity; INVOLVED IN: cell wall modification; LOCATED IN: membrane, plant-type cell wall; EXPRESSED IN: 9 plant structures; EXPRESSED DURING: 4 anthesis, C globular stage, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Carbohydrate-binding/sugar hydrolysis domain (InterPro:IPR006633), Pectinesterase, active site (InterPro:IPR018040), Pectin lyase fold/virulence factor (InterPro:IPR011050), Pectinesterase, catalytic (InterPro:IPR000070), Pectinesterase inhibitor (InterPro:IPR006501), Pectin lyase fold (InterPro:IPR012334); BEST Arabidopsis thaliana protein match is: Plant invertase/pectin methylesterase inhibitor superfamily (TAIR:AT5G51490.1); Has 2773 Blast hits to 2723 proteins in 340 species: Archae - 10; Bacteria - 616; Metazoa - 1; Fungi - 203; Plants - 1907; Viruses - 0; Other Eukaryotes - 36 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      18644061..18646606 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_130085.4 → NP_566038.1  Plant invertase/pectin methylesterase inhibitor superfamily [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566038.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O22149, Q570I2, Q9ASU4
      UniProtKB/TrEMBL
      A0A178VY55, A0A5S9X771
      Conserved Domains (3) summary
      PLN02995
      Location:7 → 511
      PLN02995; Probable pectinesterase/pectinesterase inhibitor
      TIGR01614
      Location:2 → 176
      PME_inhib; pectinesterase inhibitor domain
      pfam01095
      Location:206 → 497
      Pectinesterase; Pectinesterase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O22149.2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools