U.S. flag

An official website of the United States government

Links from GEO Profiles

    • Showing Current items.

    Entr1 endosome associated trafficking regulator 1 [ Mus musculus (house mouse) ]

    Gene ID: 68112, updated on 4-Jan-2025

    Summary

    Official Symbol
    Entr1provided by MGI
    Official Full Name
    endosome associated trafficking regulator 1provided by MGI
    Primary source
    MGI:MGI:1915362
    See related
    Ensembl:ENSMUSG00000026927 AllianceGenome:MGI:1915362
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Sdccag3; C330016H24Rik; C630038K21Rik
    Summary
    Predicted to be involved in several processes, including endocytic recycling; positive regulation of cilium assembly; and positive regulation of protein localization to cilium. Predicted to be located in endosome. Predicted to be part of retromer complex. Predicted to be active in endosome; microtubule organizing center; and midbody. Orthologous to human ENTR1 (endosome associated trafficking regulator 1). [provided by Alliance of Genome Resources, Jan 2025]
    Expression
    Ubiquitous expression in testis adult (RPKM 146.9), CNS E18 (RPKM 52.5) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Entr1 in Genome Data Viewer
    Location:
    2 A3; 2 18.88 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (26272810..26279352, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (26382798..26389340, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene predicted gene 13562 Neighboring gene caspase recruitment domain family, member 9 Neighboring gene small nuclear RNA activating complex, polypeptide 4 Neighboring gene peptidase (mitochondrial processing) alpha Neighboring gene inositol polyphosphate-5-phosphatase E Neighboring gene STARR-positive B cell enhancer ABC_E5900 Neighboring gene SEC16 homolog A, endoplasmic reticulum export factor Neighboring gene RIKEN cDNA 0610009E02 gene Neighboring gene STARR-positive B cell enhancer ABC_E1241

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 

    General gene information

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in cell division  
    involved_in cell projection organization  
    involved_in endocytic recycling  
    involved_in endocytic recycling  
    involved_in positive regulation of cilium assembly  
    involved_in positive regulation of cilium assembly  
    involved_in positive regulation of cilium assembly  
    involved_in positive regulation of protein localization to cilium  
    involved_in positive regulation of protein localization to cilium  
    involved_in positive regulation of protein localization to cilium  
    involved_in protein transport  
    involved_in regulation of cytokinesis  
    involved_in regulation of cytokinesis  
    involved_in regulation of cytokinesis  
    Component Evidence Code Pubs
    is_active_in centrosome  
    located_in centrosome  
    located_in centrosome  
    is_active_in ciliary basal body  
    located_in ciliary basal body  
    located_in ciliary basal body  
    is_active_in early endosome  
    located_in early endosome  
    located_in early endosome  
    located_in endosome  
    is_active_in midbody  
    located_in midbody  
    located_in midbody  
    is_active_in recycling endosome  
    located_in recycling endosome  
    located_in recycling endosome  
    part_of retromer complex  
    part_of retromer complex  

    General protein information

    Preferred Names
    endosome-associated-trafficking regulator 1
    Names
    serologically defined colon cancer antigen 3 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001085407.1NP_001078876.1  endosome-associated-trafficking regulator 1 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AK082787, AK163690, BY104480
      Consensus CDS
      CCDS50541.1
      UniProtKB/Swiss-Prot
      A2AIW0
      Related
      ENSMUSP00000028293.6, ENSMUST00000028293.12
      Conserved Domains (1) summary
      pfam16034
      Location:147317
      JAKMIP_CC3; JAKMIP CC3 domain
    2. NM_001085408.1NP_001078877.1  endosome-associated-trafficking regulator 1 isoform 4

      See identical proteins and their annotated locations for NP_001078877.1

      Status: VALIDATED

      Source sequence(s)
      AK163690, AW743523, BY104480
      Consensus CDS
      CCDS50540.1
      UniProtKB/Swiss-Prot
      A2AIW0
      Related
      ENSMUSP00000077133.7, ENSMUST00000077983.13
      Conserved Domains (1) summary
      pfam16034
      Location:124294
      JAKMIP_CC3; JAKMIP CC3 domain
    3. NM_026563.3NP_080839.2  endosome-associated-trafficking regulator 1 isoform 1

      See identical proteins and their annotated locations for NP_080839.2

      Status: VALIDATED

      Source sequence(s)
      AK014885, AK163690, BY104480
      Consensus CDS
      CCDS15803.2
      UniProtKB/Swiss-Prot
      A2AIW0, A2AIW1, Q3TQC5, Q6P8W2, Q8BIV5, Q8K0I8, Q9D1V2, Q9D4S1, Q9D5W1
      Related
      ENSMUSP00000109737.4, ENSMUST00000114102.10
      Conserved Domains (1) summary
      pfam16034
      Location:197367
      JAKMIP_CC3; JAKMIP CC3 domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      26272810..26279352 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030252001.1XP_030107861.1  endosome-associated-trafficking regulator 1 isoform X3

      Conserved Domains (1) summary
      TIGR02169
      Location:186285
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    2. XM_006498261.2XP_006498324.1  endosome-associated-trafficking regulator 1 isoform X1

      Conserved Domains (1) summary
      pfam15898
      Location:269357
      PRKG1_interact; cGMP-dependent protein kinase interacting domain
    3. XM_030252003.1XP_030107863.1  endosome-associated-trafficking regulator 1 isoform X5

      Conserved Domains (1) summary
      TIGR02169
      Location:106205
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    4. XM_006498262.5XP_006498325.1  endosome-associated-trafficking regulator 1 isoform X2

      UniProtKB/TrEMBL
      A2AIW3
      Related
      ENSMUSP00000109735.4, ENSMUST00000114100.10
      Conserved Domains (1) summary
      TIGR02168
      Location:228350
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    5. XM_030252002.2XP_030107862.1  endosome-associated-trafficking regulator 1 isoform X4

      Conserved Domains (1) summary
      TIGR02168
      Location:98220
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    6. XM_036162513.1XP_036018406.1  endosome-associated-trafficking regulator 1 isoform X4

      Conserved Domains (1) summary
      TIGR02168
      Location:98220
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    RNA

    1. XR_003953706.1 RNA Sequence

    2. XR_003953705.2 RNA Sequence

    3. XR_003953703.2 RNA Sequence

    4. XR_003953704.2 RNA Sequence

    5. XR_004940714.1 RNA Sequence

    6. XR_374113.2 RNA Sequence

    7. XR_374114.2 RNA Sequence

    8. XR_003953702.1 RNA Sequence

    9. XR_004940713.1 RNA Sequence

    10. XR_004940712.1 RNA Sequence

    11. XR_003953701.1 RNA Sequence

    External link. Please review our privacy policy.