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    CG11069 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42976, updated on 9-Dec-2024

    Summary

    Official Symbol
    CG11069provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039244
    Locus tag
    Dmel_CG11069
    See related
    AllianceGenome:FB:FBgn0039244
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    DmCG11069; Dmel\CG11069
    Summary
    Predicted to enable ATPase-coupled transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Predicted to be part of ATP-binding activity cassette (ABC) transporter complex. Predicted to be active in plasma membrane. Is expressed in several structures, including adult head; dorsal ectoderm; dorsal epidermis primordium; epithelium; and gut section. Human ortholog(s) of this gene implicated in arteriosclerosis; sitosterolemia 1; and sitosterolemia 2. Orthologous to human ABCG5 (ATP binding cassette subfamily G member 5). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Genomic context

    See CG11069 in Genome Data Viewer
    Location:
    96B4-96B4; 3-86 cM
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (24894742..24897613)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (20720464..20723335)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR44267 Neighboring gene Phosphatidylinositol glycan anchor biosynthesis class S

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ABC-type transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATPase-coupled transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of ATP-binding cassette (ABC) transporter complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    uncharacterized protein
    Names
    CG11069-PA
    NP_651307.2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      24894742..24897613
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_143050.2NP_651307.2  uncharacterized protein Dmel_CG11069 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651307.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MRJ2, Q9VC15
      Related
      FBpp0084089
      Conserved Domains (3) summary
      cd03234
      Location:15233
      ABCG_White; White pigment protein homolog of ABCG transporter subfamily
      COG1131
      Location:31302
      CcmA; ABC-type multidrug transport system, ATPase component [Defense mechanisms]
      cl21474
      Location:364515
      ABC2_membrane; ABC-2 type transporter