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    Zfp512b zinc finger protein 512B [ Mus musculus (house mouse) ]

    Gene ID: 269401, updated on 3-Dec-2024

    Summary

    Official Symbol
    Zfp512bprovided by MGI
    Official Full Name
    zinc finger protein 512Bprovided by MGI
    Primary source
    MGI:MGI:2685478
    See related
    Ensembl:ENSMUSG00000000823 AllianceGenome:MGI:2685478
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm632; Znf512b
    Summary
    Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of miRNA transcription. Predicted to be located in nucleoplasm. Is expressed in lung. Orthologous to human ZNF512B (zinc finger protein 512B). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in adrenal adult (RPKM 26.1), testis adult (RPKM 23.8) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Zfp512b in Genome Data Viewer
    Location:
    2 H4; 2 103.67 cM
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (181223925..181234572, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (181582103..181592972, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene DnaJ heat shock protein family (Hsp40) member C5 Neighboring gene STARR-positive B cell enhancer ABC_E3426 Neighboring gene uridine-cytidine kinase 1-like 1 Neighboring gene uridine-cytidine kinase 1-like 1, opposite strand Neighboring gene microRNA 7006 Neighboring gene STARR-positive B cell enhancer mm9_chr2:181335875-181336176 Neighboring gene sterile alpha motif domain containing 10 Neighboring gene pre-mRNA splicing factor 6 Neighboring gene STARR-seq mESC enhancer starr_06756

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001164597.2NP_001158069.1  zinc finger protein 512B isoform 4

      See identical proteins and their annotated locations for NP_001158069.1

      Status: VALIDATED

      Source sequence(s)
      AL844529
      Consensus CDS
      CCDS50855.1
      UniProtKB/TrEMBL
      B7ZCR6, Q6ZPW1
      Related
      ENSMUSP00000104417.3, ENSMUST00000108789.9
      Conserved Domains (2) summary
      PRK12323
      Location:170425
      PRK12323; DNA polymerase III subunit gamma/tau
      sd00017
      Location:573594
      ZF_C2H2; C2H2 Zn finger [structural motif]
    2. NM_001409726.1NP_001396655.1  zinc finger protein 512B isoform 1

      Status: VALIDATED

      Source sequence(s)
      AL844529
      UniProtKB/TrEMBL
      Q6PHP4
    3. NM_001409728.1NP_001396657.1  zinc finger protein 512B isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL844529
      UniProtKB/TrEMBL
      Q6PHP4
    4. NM_001409730.1NP_001396659.1  zinc finger protein 512B isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL844529
      UniProtKB/TrEMBL
      Q6PHP4
    5. NM_001409731.1NP_001396660.1  zinc finger protein 512B isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL844529
      UniProtKB/TrEMBL
      Q6PHP4
      Related
      ENSMUSP00000115601.2, ENSMUST00000128553.8
    6. NM_001409732.1NP_001396661.1  zinc finger protein 512B isoform 3

      Status: VALIDATED

      Source sequence(s)
      AL844529
      UniProtKB/TrEMBL
      Q6PHP4
    7. NM_001409733.1NP_001396662.1  zinc finger protein 512B isoform 4

      Status: VALIDATED

      Source sequence(s)
      AL844529
      UniProtKB/TrEMBL
      B7ZCR6, Q6ZPW1
    8. NM_001409734.1NP_001396663.1  zinc finger protein 512B isoform 4

      Status: VALIDATED

      Source sequence(s)
      AL844529
      UniProtKB/TrEMBL
      B7ZCR6, Q6ZPW1
    9. NM_001409735.1NP_001396664.1  zinc finger protein 512B isoform 5

      Status: VALIDATED

      Source sequence(s)
      AL844529
      UniProtKB/TrEMBL
      Q6ZPW1
    10. NM_001409736.1NP_001396665.1  zinc finger protein 512B isoform 6

      Status: VALIDATED

      Source sequence(s)
      AL844529
      UniProtKB/TrEMBL
      Q6PHP4
    11. NM_001409737.1NP_001396666.1  zinc finger protein 512B isoform 7

      Status: VALIDATED

      Source sequence(s)
      AL844529
      UniProtKB/TrEMBL
      Q6PHP4

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      181223925..181234572 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006500650.5XP_006500713.1  zinc finger protein 512B isoform X3

      Conserved Domains (2) summary
      PHA03247
      Location:141517
      PHA03247; large tegument protein UL36; Provisional
      sd00020
      Location:530559
      ZF_C2H2; C2H2 Zn finger [structural motif]
    2. XM_011239943.4XP_011238245.1  zinc finger protein 512B isoform X2

      Conserved Domains (2) summary
      PHA03247
      Location:141436
      PHA03247; large tegument protein UL36; Provisional
      sd00020
      Location:533562
      ZF_C2H2; C2H2 Zn finger [structural motif]

    RNA

    1. XR_375397.5 RNA Sequence