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    katA catalase [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 881831, updated on 11-Sep-2024

    Summary

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    Gene symbol
    katA
    Gene description
    catalase
    Locus tag
    PA4236
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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    Genomic context

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    Sequence:
    NC_002516.2 (4752260..4753708, complement)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene excinuclease ABC subunit A Neighboring gene bacterioferritin Neighboring gene 50S ribosomal protein L17 Neighboring gene DNA-directed RNA polymerase subunit alpha

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Honey-sensitive Pseudomonas aeruginosa mutants are impaired in catalase A. Bolognese F, et al. Microbiology (Reading), 2016 Sep. PMID 27516083
    2. The stringent response controls catalases in Pseudomonas aeruginosa and is required for hydrogen peroxide and antibiotic tolerance. Khakimova M, et al. J Bacteriol, 2013 May. PMID 23457248, Free PMC Article
    3. Phosphate limitation induces catalase expression in Sinorhizobium meliloti, Pseudomonas aeruginosa and Agrobacterium tumefaciens. Yuan ZC, et al. Mol Microbiol, 2005 Nov. PMID 16238634
    4. Protective role of extracellular catalase (KatA) against UVA radiation in Pseudomonas aeruginosa biofilms. Pezzoni M, et al. J Photochem Photobiol B, 2014 Feb 5. PMID 24491420
    5. Bacterioferritin A modulates catalase A (KatA) activity and resistance to hydrogen peroxide in Pseudomonas aeruginosa. Ma JF, et al. J Bacteriol, 1999 Jun. PMID 10368148, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The knockout of katA gene caused sensitivity not only to hydrogen peroxide but also to different types of honey including Manuka GMO 220 honey.
      Title: Honey-sensitive Pseudomonas aeruginosa mutants are impaired in catalase A.
    2. KatA activity is present in the matrix of P. aeruginosa biofilms.Extracellular KatA is essential in the defense of P. aeruginosa biofilms against UVA.
      Title: Protective role of extracellular catalase (KatA) against UVA radiation in Pseudomonas aeruginosa biofilms.
    3. The stringent response controls the expression of katA and katB.
      Title: The stringent response controls catalases in Pseudomonas aeruginosa and is required for hydrogen peroxide and antibiotic tolerance.
    4. Results show that growth under phosphate limitation induces catalase expression in Sinorhizobium meliloti, Pseudomonas aeruginosa and Agrobacterium tumefaciens.
      Title: Phosphate limitation induces catalase expression in Sinorhizobium meliloti, Pseudomonas aeruginosa and Agrobacterium tumefaciens.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by PseudoCAP

    Function Evidence Code Pubs
    enables catalase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    catalase
    NP_252926.1
    • Product name confidence: class 1 (Function experimentally demonstrated in P. aeruginosa)

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      4752260..4753708 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_252926.1 catalase [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_252926.1

      Status: PROVISIONAL

      Conserved Domains (1) summary
      cd08156
      Location:48 → 477
      catalase_clade_3; Clade 3 of the heme-binding enzyme catalase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O52762.1

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