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    narG respiratory nitrate reductase subunit alpha [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 879780, updated on 24-Aug-2024

    Summary

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    Gene symbol
    narG
    Gene description
    respiratory nitrate reductase subunit alpha
    Locus tag
    PA3875
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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    Genomic context

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    Sequence:
    NC_002516.2 (4338261..4342046, complement)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene respiratory nitrate reductase subunit delta Neighboring gene respiratory nitrate reductase subunit beta Neighboring gene nitrite extrusion protein 2 Neighboring gene nitrite extrusion protein 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Fosfomycin and tobramycin in combination downregulate nitrate reductase genes narG and narH, resulting in increased activity against Pseudomonas aeruginosa under anaerobic conditions. McCaughey G, et al. Antimicrob Agents Chemother, 2013 Nov. PMID 23959314, Free PMC Article
    2. The mobA gene is required for assimilatory and respiratory nitrate reduction but not xanthine dehydrogenase activity in Pseudomonas aeruginosa. Noriega C, et al. Curr Microbiol, 2005 Dec. PMID 16235022
    3. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
    4. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
    5. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Down-regulation of narG and narH expression increases the susceptibility of Pseudomonas aeruginosa towards antibiotics.
      Title: Fosfomycin and tobramycin in combination downregulate nitrate reductase genes narG and narH, resulting in increased activity against Pseudomonas aeruginosa under anaerobic conditions.
    2. mobA mutant was deficient in both assimilatory and respiratory nitrate reductase activities, whereas xanthine dehydrogenase activity remained unaffected.
      Title: The mobA gene is required for assimilatory and respiratory nitrate reduction but not xanthine dehydrogenase activity in Pseudomonas aeruginosa.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    General protein information

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    Preferred Names
    respiratory nitrate reductase subunit alpha
    NP_252564.1
    • Product name confidence: class 2 (High similarity to functionally studied protein)

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      4338261..4342046 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_252564.1 respiratory nitrate reductase subunit alpha [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_252564.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      G3XCX1, O54043
      Conserved Domains (1) summary
      COG5013
      Location:1 → 1239
      NarG; Nitrate reductase alpha subunit [Energy production and conversion, Inorganic ion transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version

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