U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    thrH phosphoserine phosphatase [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 877969, updated on 11-Sep-2024

    Summary

    Go to the top of the page Help
    Gene symbol
    thrH
    Gene description
    phosphoserine phosphatase
    Locus tag
    PA1757
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Sequence:
    NC_002516.2 (1896630..1897247)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene phosphoadenosine phosphosulfate reductase Neighboring gene para-aminobenzoate synthase component I Neighboring gene transcriptional regulator

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Direct detection and kinetic analysis of covalent intermediate formation in the 4-amino-4-deoxychorismate synthase catalyzed reaction. He Z, et al. Biochemistry, 2006 Apr 18. PMID 16605270
    2. ThrH, a homoserine kinase isozyme with in vivo phosphoserine phosphatase activity in Pseudomonas aeruginosa. Patte JC, et al. Microbiology (Reading), 1999 Apr. PMID 10220164
    3. p-Aminobenzoate synthesis in Escherichia coli: purification and characterization of PabB as aminodeoxychorismate synthase and enzyme X as aminodeoxychorismate lyase. Ye QZ, et al. Proc Natl Acad Sci U S A, 1990 Dec. PMID 2251281, Free PMC Article
    4. The thrH gene product of Pseudomonas aeruginosa is a dual activity enzyme with a novel phosphoserine:homoserine phosphotransferase activity. Singh SK, et al. J Biol Chem, 2004 Mar 26. PMID 14699121
    5. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by PseudoCAP

    Function Evidence Code Pubs
    enables 4-amino-4-deoxychorismate synthase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables homoserine kinase activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables magnesium ion binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables phosphoserine:homoserine phosphotransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within L-serine biosynthetic process IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within tetrahydrofolate biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    acts_upstream_of_or_within threonine biosynthetic process IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within threonine biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    phosphoserine phosphatase
    NP_250448.1
    • Product name confidence: class 1 (Function experimentally demonstrated in P. aeruginosa)

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      1896630..1897247
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_250448.1 phosphoserine phosphatase [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_250448.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      Q9ZEX8
      Conserved Domains (1) summary
      PRK13582
      Location:1 → 205
      thrH; bifunctional phosphoserine phosphatase/homoserine phosphotransferase ThrH
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9I2Y2.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases