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    laf1 clr6 L-associated factor 1 Laf1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541650, updated on 14-Nov-2024

    Summary

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    Official Symbol
    laf1
    Official Full Name
    clr6 L-associated factor 1 Laf1
    Primary source
    PomBase:SPAC14C4.12c
    Locus tag
    SPOM_SPAC14C4.12C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See laf1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (5250520..5252234, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene protein mug5 Neighboring gene Nudix family hydrolase Neighboring gene cell wall glucan endo-1,3-alpha-glucosidase Agn1 Neighboring gene ncRNA Neighboring gene polyphosphate synthetase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene RFC-like checkpoint protein Rad17

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A novel histone deacetylase complex in the control of transcription and genome stability. Zilio N, et al. Mol Cell Biol, 2014 Sep 15. PMID 25002536, Free PMC Article
    2. Chromatin Central: towards the comparative proteome by accurate mapping of the yeast proteomic environment. Shevchenko A, et al. Genome Biol, 2008. PMID 19040720, Free PMC Article
    3. Posttranslational Arginylation Enzyme Arginyltransferase1 Shows Genetic Interactions With Specific Cellular Pathways in vivo. Wiley DJ, et al. Front Physiol, 2020. PMID 32435206, Free PMC Article
    4. A genetic screen to discover pathways affecting cohesin function in Schizosaccharomyces pombe identifies chromatin effectors. Chen Z, et al. G3 (Bethesda), 2012 Oct. PMID 23050226, Free PMC Article
    5. Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts. Anver S, et al. EMBO Rep, 2014 Aug. PMID 24957674, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables DNA binding ISM
    Inferred from Sequence Model
    more info
    		  
    enables chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transcription coactivator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in chromatin remodeling IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in chromatin remodeling IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transcription initiation-coupled chromatin remodeling IC
    Inferred by Curator
    more info
    		  
    Component Evidence Code Pubs
    part_of Rpd3L complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of Rpd3L-Expanded complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of Rpd3L-Expanded complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    clr6 L-associated factor 1 Laf1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      5250520..5252234 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001020349.3 → NP_594917.1  clr6 L-associated factor 1 Laf1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594917.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O13719
      Conserved Domains (1) summary
      pfam04433
      Location:216 → 296
      SWIRM; SWIRM domain
    Nucleotide Protein
    Heading Accession and Version

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