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    EDA36 Pyridoxal phosphate (PLP)-dependent transferases superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 827024, updated on 18-Sep-2024

    Summary

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    Official Symbol
    EDA36
    Official Full Name
    Pyridoxal phosphate (PLP)-dependent transferases superfamily protein
    Primary source
    TAIR:AT4G13890
    Locus tag
    AT4G13890
    See related
    Araport:AT4G13890
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    EDA37; EMBRYO SAC DEVELOPMENT ARREST 36; EMBRYO SAC DEVELOPMENT ARREST 37; F18A5.280; F18A5_280; SERINE HYDROXYMETHYLTRANSFERASE 5; SHM5
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    Genomic context

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    See EDA36 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    3
    Sequence:
    Chromosome: 4; NC_003075.7 (8031972..8033731, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene Polynucleotidyl transferase, ribonuclease H-like superfamily protein Neighboring gene ncRNA Neighboring gene miscRNA Neighboring gene miscRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A collection of Ds insertional mutants associated with defects in male gametophyte development and function in Arabidopsis thaliana. Boavida LC, et al. Genetics, 2009 Apr. PMID 19237690, Free PMC Article
    2. Genetic and molecular identification of genes required for female gametophyte development and function in Arabidopsis. Pagnussat GC, et al. Development, 2005 Feb. PMID 15634699
    3. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article
    4. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    NM_001340891.1
    NM_117463.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables glycine hydroxymethyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables pyridoxal phosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in glycine biosynthetic process from serine IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within polar nucleus fusion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within pollen development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in tetrahydrofolate interconversion IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol HDA PubMed 

    General protein information

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    Preferred Names
    Pyridoxal phosphate (PLP)-dependent transferases superfamily protein
    NP_193125.1
    • EMBRYO SAC DEVELOPMENT ARREST 37 (EDA36); FUNCTIONS IN: pyridoxal phosphate binding, glycine hydroxymethyltransferase activity, catalytic activity; INVOLVED IN: glycine metabolic process, polar nucleus fusion, L-serine metabolic process, pollen development; LOCATED IN: cellular_component unknown; EXPRESSED IN: male gametophyte, pollen tube; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage; CONTAINS InterPro DOMAIN/s: Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Serine hydroxymethyltransferase, pyridoxal phosphate binding site (InterPro:IPR019798), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421), Serine hydroxymethyltransferase (InterPro:IPR001085); BEST Arabidopsis thaliana protein match is: serine hydroxymethyltransferase 4 (TAIR:AT4G13930.1); Has 11625 Blast hits to 11598 proteins in 2846 species: Archae - 258; Bacteria - 6397; Metazoa - 338; Fungi - 287; Plants - 371; Viruses - 6; Other Eukaryotes - 3968 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      8031972..8033731 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_117463.3 → NP_193125.1  Pyridoxal phosphate (PLP)-dependent transferases superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_193125.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SVM4
      UniProtKB/TrEMBL
      A0A5S9XS52, A0A7G2EXT8
      Conserved Domains (2) summary
      PLN03226
      Location:1 → 468
      PLN03226; serine hydroxymethyltransferase; Provisional
      cl18945
      Location:12 → 412
      AAT_I; Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the ...

    2. NM_001340891.1 → NP_001328680.1  Pyridoxal phosphate (PLP)-dependent transferases superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B5D5, A0A5S9XS52, A0A7G2EXT8
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SVM4.1

    Gene LinkOut

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