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    ZNHIT2 zinc finger HIT-type containing 2 [ Homo sapiens (human) ]

    Gene ID: 741, updated on 10-Dec-2024

    Summary

    Official Symbol
    ZNHIT2provided by HGNC
    Official Full Name
    zinc finger HIT-type containing 2provided by HGNC
    Primary source
    HGNC:HGNC:1177
    See related
    Ensembl:ENSG00000174276 MIM:604575; AllianceGenome:HGNC:1177
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    FON; C11orf5
    Summary
    Predicted to enable metal ion binding activity. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Genomic context

    See ZNHIT2 in Genome Data Viewer
    Location:
    11q13.1
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (65116403..65117701, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (65109682..65110980, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (64883875..64885173, complement)

    Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:64863491-64864285 Neighboring gene VPS51 subunit of GARP complex Neighboring gene Sharpr-MPRA regulatory region 6888 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:64877599-64878526 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:64878527-64879452 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4942 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3509 Neighboring gene transmembrane 7 superfamily member 2 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:64882956-64883501 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:64883502-64884046 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:64884593-64885136 Neighboring gene Sharpr-MPRA regulatory region 3974 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4943 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4944 Neighboring gene FAU ubiquitin like and ribosomal protein S30 fusion Neighboring gene mitochondrial ribosomal protein L49 Neighboring gene synoviolin 1

    Genomic regions, transcripts, and products

    Interactions

    General gene information

    Clone Names

    • MGC120285, MGC120286

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables metal ion binding  
    enables protein binding PubMed 

    General protein information

    Preferred Names
    zinc finger HIT domain-containing protein 2
    Names
    zinc finger, HIT domain containing 2
    zinc finger, HIT type 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_014205.4NP_055020.1  zinc finger HIT domain-containing protein 2

      See identical proteins and their annotated locations for NP_055020.1

      Status: VALIDATED

      Source sequence(s)
      BC052240, HY200798
      Consensus CDS
      CCDS8094.1
      UniProtKB/Swiss-Prot
      Q3SY14, Q8IUV0, Q9UHR6
      UniProtKB/TrEMBL
      Q53FD1, Q53FF6
      Related
      ENSP00000308548.4, ENST00000310597.6
      Conserved Domains (1) summary
      pfam04438
      Location:336
      zf-HIT; HIT zinc finger

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

      Range
      65116403..65117701 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060935.1 Alternate T2T-CHM13v2.0

      Range
      65109682..65110980 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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