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    PFA-DSP2 Phosphotyrosine protein phosphatases superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817858, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PFA-DSP2
    Official Full Name
    Phosphotyrosine protein phosphatases superfamily protein
    Primary source
    TAIR:AT2G32960
    Locus tag
    AT2G32960
    See related
    Araport:AT2G32960
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtPFA-DSP2; plant and fungi atypical dual-specificity phosphatase 2; T21L14.10; T21L14_10
    Summary
    Encodes an atypical dual-specificity phosphatase.
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    Genomic context

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    See PFA-DSP2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    6
    Sequence:
    Chromosome: 2; NC_003071.7 (13987669..13990994)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Argonaute family protein Neighboring gene Transducin/WD40 repeat-like superfamily protein Neighboring gene G1/S-specific cyclin-E protein Neighboring gene HAUS augmin-like complex subunit

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis PFA-DSP-Type Phosphohydrolases Target Specific Inositol Pyrophosphate Messengers. Gaugler P, et al. Biochemistry, 2022 Jun 21. PMID 35640071, Free PMC Article
    2. Phylogenetic and genetic linkage between novel atypical dual-specificity phosphatases from non-metazoan organisms. Romá-Mateo C, et al. Mol Genet Genomics, 2011 Apr. PMID 21409566
    3. Extensive signal integration by the phytohormone protein network. Altmann M, et al. Nature, 2020 Jul. PMID 32612234
    4. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    5. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_128856.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein tyrosine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within dephosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Phosphotyrosine protein phosphatases superfamily protein
    NP_180855.2
    • Phosphotyrosine protein phosphatases superfamily protein; FUNCTIONS IN: phosphatase activity, protein tyrosine phosphatase activity, catalytic activity; INVOLVED IN: dephosphorylation; LOCATED IN: cellular_component unknown; CONTAINS InterPro DOMAIN/s: Protein-tyrosine phosphatase, active site (InterPro:IPR016130), Dual-specific/protein-tyrosine phosphatase, conserved region (InterPro:IPR000387), Protein-tyrosine phosphatase, dual specificity phosphatase, eukaryotic (InterPro:IPR020428), Protein-tyrosine phosphatase, SIW14-like (InterPro:IPR004861); BEST Arabidopsis thaliana protein match is: Phosphotyrosine protein phosphatases superfamily protein (TAIR:AT1G05000.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      13987669..13990994
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_128856.5 → NP_180855.2  Phosphotyrosine protein phosphatases superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_180855.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O48769, Q84MD6
      UniProtKB/TrEMBL
      A0A178VUQ8, A0A5S9X3E8, A0A654EZQ4
      Conserved Domains (1) summary
      cd14528
      Location:61 → 241
      PFA-DSP_Siw14; atypical dual specificity phosphatases similar to yeast Siw14
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q84MD6.1

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