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    3-oxo-5-alpha-steroid 4-dehydrogenase family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 816152, updated on 18-Sep-2024

    Summary

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    Official Full Name
    3-oxo-5-alpha-steroid 4-dehydrogenase family protein
    Primary source
    TAIR:AT2G16530
    Locus tag
    AT2G16530
    See related
    Araport:AT2G16530
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F1P15.9; F1P15_9
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    Genomic context

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    Location:
    chromosome: 2
    Exon count:
    7
    Sequence:
    Chromosome: 2; NC_003071.7 (7162931..7165410, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene ATPase, F0/V0 complex, subunit C protein Neighboring gene ncRNA Neighboring gene RING/U-box protein with C6HC-type zinc finger protein Neighboring gene maternally expressed family protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. POLYPRENOL REDUCTASE2 Deficiency Is Lethal in Arabidopsis Due to Male Sterility. Jozwiak A, et al. Plant Cell, 2015 Dec. PMID 26628744, Free PMC Article
    2. Mapping the Arabidopsis organelle proteome. Dunkley TP, et al. Proc Natl Acad Sci U S A, 2006 Apr 25. PMID 16618929, Free PMC Article
    3. Isolation and proteomic characterization of the Arabidopsis Golgi defines functional and novel components involved in plant cell wall biosynthesis. Parsons HT, et al. Plant Physiol, 2012 May. PMID 22430844, Free PMC Article
    4. Putative glycosyltransferases and other plant Golgi apparatus proteins are revealed by LOPIT proteomics. Nikolovski N, et al. Plant Physiol, 2012 Oct. PMID 22923678, Free PMC Article
    5. Border control--a membrane-linked interactome of Arabidopsis. Jones AM, et al. Science, 2014 May 16. PMID 24833385

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    NM_001335478.1
    NM_001335479.1
    NM_001335480.1
    NM_127207.4
    NM_201745.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables 3-oxo-5-alpha-steroid 4-dehydrogenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables polyprenol reductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in dolichol-linked oligosaccharide biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within protein N-linked glycosylation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus HDA PubMed 
    located_in endoplasmic reticulum HDA PubMed 
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    3-oxo-5-alpha-steroid 4-dehydrogenase family protein
    NP_565389.1
    • 3-oxo-5-alpha-steroid 4-dehydrogenase family protein; FUNCTIONS IN: oxidoreductase activity, acting on the CH-CH group of donors, 3-oxo-5-alpha-steroid 4-dehydrogenase activity; INVOLVED IN: lipid metabolic process; LOCATED IN: endoplasmic reticulum; EXPRESSED IN: callus; CONTAINS InterPro DOMAIN/s: 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal (InterPro:IPR001104); BEST Arabidopsis thaliana protein match is: 3-oxo-5-alpha-steroid 4-dehydrogenase family protein (TAIR:AT1G72590.1); Has 1047 Blast hits to 1045 proteins in 211 species: Archae - 0; Bacteria - 24; Metazoa - 384; Fungi - 161; Plants - 181; Viruses - 0; Other Eukaryotes - 297 (source: NCBI BLink).
    NP_973474.1
    • 3-oxo-5-alpha-steroid 4-dehydrogenase family protein; FUNCTIONS IN: oxidoreductase activity, acting on the CH-CH group of donors, 3-oxo-5-alpha-steroid 4-dehydrogenase activity; INVOLVED IN: lipid metabolic process; LOCATED IN: endoplasmic reticulum; EXPRESSED IN: callus; CONTAINS InterPro DOMAIN/s: 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal (InterPro:IPR001104); BEST Arabidopsis thaliana protein match is: 3-oxo-5-alpha-steroid 4-dehydrogenase family protein (TAIR:AT1G72590.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      7162931..7165410 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_127207.4 → NP_565389.1  3-oxo-5-alpha-steroid 4-dehydrogenase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565389.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q3EBZ6, Q941B4, Q9SI62
      UniProtKB/TrEMBL
      A0A5S9WYG4, A0A654EUV8, A0A7G2E6P0
      Conserved Domains (1) summary
      PLN03164
      Location:21 → 343
      PLN03164; 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal domain containing protein; Provisional

    2. NM_001335478.1 → NP_001325182.1  3-oxo-5-alpha-steroid 4-dehydrogenase family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B2E4, A0A7G2E6P0

    3. NM_001335479.1 → NP_001325183.1  3-oxo-5-alpha-steroid 4-dehydrogenase family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q3EBZ6, Q941B4, Q9SI62
      UniProtKB/TrEMBL
      A0A5S9WYG4, A0A654EUV8, A0A7G2E6P0
      Conserved Domains (1) summary
      PLN03164
      Location:21 → 343
      PLN03164; 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal domain containing protein; Provisional

    4. NM_001335480.1 → NP_001325184.1  3-oxo-5-alpha-steroid 4-dehydrogenase family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B2I5, A0A7G2E6P0

    5. NM_201745.2 → NP_973474.1  3-oxo-5-alpha-steroid 4-dehydrogenase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_973474.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A7G2E6P0
      Conserved Domains (1) summary
      PLN03164
      Location:21 → 342
      PLN03164; 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal domain containing protein; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SI62.2

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