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    Ocel1 occludin/ELL domain containing 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 290628, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Ocel1provided by RGD
    Official Full Name
    occludin/ELL domain containing 1provided by RGD
    Primary source
    RGD:1565407
    See related
    EnsemblRapid:ENSRNOG00000032575 AllianceGenome:RGD:1565407
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1563236; RGD1565407
    Summary
    Predicted to be involved in bicellular tight junction assembly. Predicted to be active in apical plasma membrane; bicellular tight junction; and cytoplasmic vesicle. Orthologous to human OCEL1 (occludin/ELL domain containing 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Kidney (RPKM 54.2), Thymus (RPKM 53.8) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Ocel1 in Genome Data Viewer
    Location:
    16p14
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 16 NC_086034.1 (18076428..18079068)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (18042037..18045080)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (19766728..19769034)

    Chromosome 16 - NC_086034.1Genomic Context describing neighboring genes Neighboring gene myosin IXb Neighboring gene unconventional SNARE in the ER 1 Neighboring gene nuclear receptor subfamily 2, group F, member 6 Neighboring gene USH1 protein network component harmonin binding protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Gene and alternative splicing annotation with AIR. Florea L, et al. Genome Res, 2005 Jan. PMID 15632090, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC189548

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in bicellular tight junction assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in apical plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in bicellular tight junction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytoplasmic vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    occludin/ELL domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106065.1 → NP_001099535.1  occludin/ELL domain-containing protein 1

      See identical proteins and their annotated locations for NP_001099535.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474031
      UniProtKB/TrEMBL
      A6K9S4, D3ZE98
      Related
      ENSRNOP00000048493.4, ENSRNOT00000051802.5
      Conserved Domains (1) summary
      pfam07303
      Location:113 → 214
      Occludin_ELL; Occludin homology domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086034.1 Reference GRCr8

      Range
      18076428..18079068
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008771079.4 → XP_008769301.1  occludin/ELL domain-containing protein 1 isoform X2

      Conserved Domains (1) summary
      pfam07303
      Location:116 → 162
      Occludin_ELL; Occludin homology domain

    2. XM_006252856.5 → XP_006252918.1  occludin/ELL domain-containing protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006252918.1

      UniProtKB/TrEMBL
      B5DFM2
      Conserved Domains (1) summary
      pfam07303
      Location:116 → 252
      Occludin_ELL; Occludin homology domain

    3. XM_039094292.2 → XP_038950220.1  occludin/ELL domain-containing protein 1 isoform X3

      Conserved Domains (1) summary
      pfam07303
      Location:113 → 183
      Occludin_ELL; Occludin homology domain

    4. XM_008771080.4 → XP_008769302.1  occludin/ELL domain-containing protein 1 isoform X4

      See identical proteins and their annotated locations for XP_008769302.1

      UniProtKB/TrEMBL
      A6K9S5, A6K9S6
      Related
      ENSRNOP00000106130.1, ENSRNOT00000151196.1
    Nucleotide Protein Strain
    Heading Accession and Version

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