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    Tmem87a transmembrane protein 87A [ Rattus norvegicus (Norway rat) ]

    Gene ID: 366170, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Tmem87aprovided by RGD
    Official Full Name
    transmembrane protein 87Aprovided by RGD
    Primary source
    RGD:1309417
    See related
    EnsemblRapid:ENSRNOG00000008455 AllianceGenome:RGD:1309417
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1309417
    Summary
    Predicted to be involved in cellular response to mechanical stimulus; detection of mechanical stimulus involved in sensory perception of touch; and retrograde transport, endosome to Golgi. Predicted to be located in plasma membrane and ruffle. Predicted to be active in Golgi cisterna membrane. Orthologous to human TMEM87A (transmembrane protein 87A). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Thymus (RPKM 231.8), Lung (RPKM 210.3) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Tmem87a in Genome Data Viewer
    Location:
    3q35
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (127761490..127807314, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (107307726..107353571, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (112128138..112174097, complement)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene phospholipase A2, group IVF Neighboring gene ribosomal protein S25, pseudogene 11 Neighboring gene VPS39 subunit of HOPS complex Neighboring gene glucosidase, alpha; neutral C Neighboring gene uncharacterized LOC108350445 Neighboring gene small nucleolar RNA SNORA15 Neighboring gene calpain 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Post-Golgi anterograde transport requires GARP-dependent endosome-to-TGN retrograde transport. Hirata T, et al. Mol Biol Cell, 2015 Sep 1. PMID 26157166, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    NOT enables mechanosensitive potassium channel activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in cellular response to mechanical stimulus ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in detection of mechanical stimulus involved in sensory perception of touch ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in retrograde transport, endosome to Golgi IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within retrograde transport, endosome to Golgi ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in Golgi cisterna membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi cisterna membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in ruffle ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    transmembrane protein 87A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001427730.1 → NP_001414659.1  transmembrane protein 87A precursor

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003
      UniProtKB/TrEMBL
      A0A8I6GIL4
      Related
      ENSRNOP00000090087.1, ENSRNOT00000105742.2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      127761490..127807314 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063284283.1 → XP_063140353.1  transmembrane protein 87A isoform X6

    2. XM_063284279.1 → XP_063140349.1  transmembrane protein 87A isoform X2

      UniProtKB/TrEMBL
      A0A8I6GIL4

    3. XM_063284280.1 → XP_063140350.1  transmembrane protein 87A isoform X3

    4. XM_063284278.1 → XP_063140348.1  transmembrane protein 87A isoform X1

      UniProtKB/TrEMBL
      A0A8I6ACY3
      Related
      ENSRNOP00000091883.1, ENSRNOT00000100419.2

    5. XM_063284281.1 → XP_063140351.1  transmembrane protein 87A isoform X4

    6. XM_063284282.1 → XP_063140352.1  transmembrane protein 87A isoform X5

    RNA

    1. XR_010064674.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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