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    Cdh16 cadherin 16 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 307614, updated on 3-Dec-2024

    Summary

    Official Symbol
    Cdh16provided by RGD
    Official Full Name
    cadherin 16provided by RGD
    Primary source
    RGD:1311638
    See related
    EnsemblRapid:ENSRNOG00000012222 AllianceGenome:RGD:1311638
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable calcium ion binding activity. Predicted to be involved in cell adhesion. Predicted to act upstream of or within calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules. Predicted to be located in basolateral plasma membrane. Predicted to be active in plasma membrane. Orthologous to human CDH16 (cadherin 16). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward (RPKM 1947.6) See more
    Orthologs
    NEW
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    Genomic context

    See Cdh16 in Genome Data Viewer
    Location:
    19p14
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (367202..377710)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (360824..371008)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (568329..578513)

    Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene cytosolic iron-sulfur assembly component 2B Neighboring gene RRAD, Ras related glycolysis inhibitor and calcium channel regulator Neighboring gene uncharacterized LOC120098574 Neighboring gene pyruvate dehydrogenase phosphatase catalytic subunit 2 Neighboring gene uncharacterized LOC134483518

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in basolateral plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001012055.1NP_001012055.1  cadherin-16 precursor

      See identical proteins and their annotated locations for NP_001012055.1

      Status: PROVISIONAL

      Source sequence(s)
      BC081996
      UniProtKB/TrEMBL
      A6JXU7, G3V7L4, Q66H67
      Related
      ENSRNOP00000016419.4, ENSRNOT00000016419.8
      Conserved Domains (2) summary
      cd11304
      Location:344447
      Cadherin_repeat; Cadherin tandem repeat domain
      smart00112
      Location:268336
      CA; Cadherin repeats

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086037.1 Reference GRCr8

      Range
      367202..377710
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063277976.1XP_063134046.1  cadherin-16 isoform X2

      UniProtKB/TrEMBL
      A0A8I5Y838, A6JXU7, G3V7L4
      Related
      ENSRNOP00000078051.1, ENSRNOT00000094878.2
    2. XM_063277975.1XP_063134045.1  cadherin-16 isoform X1

      UniProtKB/TrEMBL
      A6JXU7, G3V7L4