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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_130424.3 → NP_569108.2 transmembrane protease serine 2
See identical proteins and their annotated locations for NP_569108.2
Status: VALIDATED
- Source sequence(s)
-
JAXUCZ010000011
- UniProtKB/TrEMBL
- F7EQ71, Q6P7D7, Q920K3
- Related
- ENSRNOP00000062828.1, ENSRNOT00000066413.5
- Conserved Domains (4) summary
-
- smart00020
Location:253 → 482
- Tryp_SPc; Trypsin-like serine protease
- cd00112
Location:112 → 147
- LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
- cd00190
Location:254 → 485
- Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
- pfam15494
Location:152 → 247
- SRCR_2; Scavenger receptor cysteine-rich domain
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCr8
Genomic
-
NC_086029.1 Reference GRCr8
- Range
-
50403707..50443224 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_008768547.4 → XP_008766769.1 transmembrane protease serine 2 isoform X1
See identical proteins and their annotated locations for XP_008766769.1
- UniProtKB/TrEMBL
-
Q920K3
- Conserved Domains (4) summary
-
- smart00020
Location:253 → 482
- Tryp_SPc; Trypsin-like serine protease
- cd00112
Location:112 → 147
- LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
- cd00190
Location:254 → 485
- Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
- pfam15494
Location:152 → 247
- SRCR_2; Scavenger receptor cysteine-rich domain
-
XM_008768548.4 → XP_008766770.1 transmembrane protease serine 2 isoform X1
See identical proteins and their annotated locations for XP_008766770.1
- UniProtKB/TrEMBL
-
Q920K3
- Conserved Domains (4) summary
-
- smart00020
Location:253 → 482
- Tryp_SPc; Trypsin-like serine protease
- cd00112
Location:112 → 147
- LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
- cd00190
Location:254 → 485
- Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
- pfam15494
Location:152 → 247
- SRCR_2; Scavenger receptor cysteine-rich domain
-
XM_063270250.1 → XP_063126320.1 transmembrane protease serine 2 isoform X2
- UniProtKB/TrEMBL
- F7EQ71, Q6P7D7