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    SK18 E3 ubiquitin ligase SCF complex subunit SKP1/ASK1 family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 837562, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SK18
    Official Full Name
    E3 ubiquitin ligase SCF complex subunit SKP1/ASK1 family protein
    Primary source
    TAIR:AT1G10230
    Locus tag
    AT1G10230
    See related
    Araport:AT1G10230
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ASK18; F14N23.11; F14N23_11; SKP1-like 18
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    Genomic context

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    See SK18 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    1
    Sequence:
    Chromosome: 1; NC_003070.9 (3355675..3356151)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene ZCF37 Neighboring gene transmembrane protein Neighboring gene FAR1-related sequence 11 Neighboring gene paired amphipathic helix Sin3-like protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arsenite provides a selective signal that coordinates arsenate uptake and detoxification through the regulation of PHR1 stability in Arabidopsis. Navarro C, et al. Mol Plant, 2021 Sep 6. PMID 34048950
    2. SKP2A, an F-box protein that regulates cell division, is degraded via the ubiquitin pathway. Jurado S, et al. Plant J, 2008 Mar. PMID 18036202
    3. EDL3 is an F-box protein involved in the regulation of abscisic acid signalling in Arabidopsis thaliana. Koops P, et al. J Exp Bot, 2011 Nov. PMID 21831845, Free PMC Article
    4. An F-box gene, CPR30, functions as a negative regulator of the defense response in Arabidopsis. Gou M, et al. Plant J, 2009 Dec. PMID 19682297
    5. The Arabidopsis F-box protein SKP1-INTERACTING PARTNER 31 modulates seed maturation and seed vigor by targeting JASMONATE ZIM DOMAIN proteins independently of jasmonic acid-isoleucine. Varshney V, et al. Plant Cell, 2023 Sep 27. PMID 37462265, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_100897.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    E3 ubiquitin ligase SCF complex subunit SKP1/ASK1 family protein
    NP_563864.2
    • SKP1-like 18 (SK18); FUNCTIONS IN: ubiquitin-protein ligase activity, protein binding; INVOLVED IN: ubiquitin-dependent protein catabolic process; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: E3 ubiquitin ligase, SCF complex, Skp subunit (InterPro:IPR016897), SKP1 component, dimerisation (InterPro:IPR016072), SKP1 component (InterPro:IPR001232), BTB/POZ fold (InterPro:IPR011333), SKP1 component, POZ (InterPro:IPR016073); BEST Arabidopsis thaliana protein match is: SKP1-like 15 (TAIR:AT3G25650.1); Has 1421 Blast hits to 1417 proteins in 266 species: Archae - 0; Bacteria - 0; Metazoa - 533; Fungi - 174; Plants - 532; Viruses - 11; Other Eukaryotes - 171 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      3355675..3356151
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_100897.3 → NP_563864.2  E3 ubiquitin ligase SCF complex subunit SKP1/ASK1 family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4I4A0, Q8LC82, Q9SY65
      UniProtKB/TrEMBL
      A0A178VZR0, A0A5S9TM59, A0A654E8K7
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SY65.2

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