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    Depp1 DEPP autophagy regulator 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 500300, updated on 2-Nov-2024

    Summary

    Official Symbol
    Depp1provided by RGD
    Official Full Name
    DEPP autophagy regulator 1provided by RGD
    Primary source
    RGD:1565700
    See related
    EnsemblRapid:ENSRNOG00000023465 AllianceGenome:RGD:1565700
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Depp
    Summary
    Predicted to be involved in regulation of autophagy. Predicted to be located in peroxisome. Predicted to be active in mitochondrion. Orthologous to human DEPP1 (DEPP autophagy regulator 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Heart (RPKM 189.7), Liver (RPKM 101.1) and 6 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Depp1 in Genome Data Viewer
    Location:
    4q42
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (151583105..151585455)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (149910794..149913013)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (148780330..148784566)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene transfer RNA cysteine (anticodon GCA) 29 Neighboring gene zinc finger protein 422 Neighboring gene Ras association domain family member 4 Neighboring gene transmembrane protein 72 Neighboring gene small nucleolar RNA SNORA17

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in regulation of autophagy IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of autophagy IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of autophagy ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    located_in peroxisome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in peroxisome ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    protein DEPP
    Names
    DEPP1, autophagy regulator
    decidual protein induced by progesterone

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024334.2NP_001019505.2  protein DEPP

      See identical proteins and their annotated locations for NP_001019505.2

      Status: PROVISIONAL

      Source sequence(s)
      BC087112
      UniProtKB/Swiss-Prot
      Q5BMD4, Q5PQM5
      UniProtKB/TrEMBL
      A0A0G2JSM9, A6IL27
      Conserved Domains (1) summary
      pfam15343
      Location:25205
      DEPP; Decidual protein induced by progesterone family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      151583105..151585455
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006237197.5XP_006237259.1  protein DEPP isoform X1

      See identical proteins and their annotated locations for XP_006237259.1

      UniProtKB/Swiss-Prot
      Q5BMD4, Q5PQM5
      UniProtKB/TrEMBL
      A0A0G2JSM9, A6IL27
      Conserved Domains (1) summary
      pfam15343
      Location:25205
      DEPP; Decidual protein induced by progesterone family
    2. XM_006237196.5XP_006237258.1  protein DEPP isoform X1

      See identical proteins and their annotated locations for XP_006237258.1

      UniProtKB/Swiss-Prot
      Q5BMD4, Q5PQM5
      UniProtKB/TrEMBL
      A0A0G2JSM9, A6IL27
      Related
      ENSRNOP00000018133.3, ENSRNOT00000018133.7
      Conserved Domains (1) summary
      pfam15343
      Location:25205
      DEPP; Decidual protein induced by progesterone family