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    Mrps25 mitochondrial ribosomal protein S25 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 297459, updated on 27-Nov-2024

    Summary

    Official Symbol
    Mrps25provided by RGD
    Official Full Name
    mitochondrial ribosomal protein S25provided by RGD
    Primary source
    RGD:1308770
    See related
    EnsemblRapid:ENSRNOG00000010912 AllianceGenome:RGD:1308770
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Shd10
    Summary
    Predicted to be a structural constituent of ribosome. Predicted to be part of mitochondrial small ribosomal subunit. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 50. Orthologous to human MRPS25 (mitochondrial ribosomal protein S25). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Kidney (RPKM 392.7), Heart (RPKM 330.2) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Mrps25 in Genome Data Viewer
    Location:
    4q34
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (126225449..126237212, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (124668320..124680086, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (124036654..124048417, complement)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene FYVE, RhoGEF and PH domain containing 5 Neighboring gene uncharacterized LOC134486612 Neighboring gene nuclear receptor subfamily 2, group C, member 2 Neighboring gene rabenosyn, RAB effector Neighboring gene uncharacterized LOC103692187 Neighboring gene uncharacterized LOC134486818 Neighboring gene thyrotropin releasing hormone

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of mitochondrial small ribosomal subunit ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    small ribosomal subunit protein mS25
    Names
    28S ribosomal protein S25, mitochondrial
    MRP-S25
    S25mt
    NP_001020579.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025408.1NP_001020579.1  small ribosomal subunit protein mS25

      See identical proteins and their annotated locations for NP_001020579.1

      Status: PROVISIONAL

      Source sequence(s)
      BC097381
      UniProtKB/Swiss-Prot
      Q4QR80
      UniProtKB/TrEMBL
      A6IBC2
      Related
      ENSRNOP00000014933.4, ENSRNOT00000014933.7
      Conserved Domains (1) summary
      smart00916
      Location:43107
      L51_S25_CI-B8; Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      126225449..126237212 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)