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    Serf2 small EDRK-rich factor 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 502663, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Serf2provided by RGD
    Official Full Name
    small EDRK-rich factor 2provided by RGD
    Primary source
    RGD:1588368
    See related
    EnsemblRapid:ENSRNOG00000064233 AllianceGenome:RGD:1588368
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in protein destabilization. Orthologous to human SERF2 (small EDRK-rich factor 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 868.4), Muscle (RPKM 604.3) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Serf2 in Genome Data Viewer
    Location:
    3q35
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (128880681..128884457)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (108426960..108430736)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (113415757..113419417)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene protein disulfide isomerase family A, member 3 Neighboring gene U6 spliceosomal RNA Neighboring gene elongation factor for RNA polymerase II 3 Neighboring gene serine incorporator 4 Neighboring gene Huntingtin interacting protein K Neighboring gene microfibrillar-associated protein 1A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Identification of MOAG-4/SERF as a regulator of age-related proteotoxicity. van Ham TJ, et al. Cell, 2010 Aug 20. PMID 20723760
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in protein destabilization ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    small EDRK-rich factor 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001098782.1 → NP_001092252.1  small EDRK-rich factor 2 isoform 2

      See identical proteins and their annotated locations for NP_001092252.1

      Status: VALIDATED

      Source sequence(s)
      BC081918
      Conserved Domains (1) summary
      pfam04419
      Location:1 → 37
      4F5; 4F5 protein family

    2. NM_001401909.1 → NP_001388838.1  small EDRK-rich factor 2 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003
      Related
      ENSRNOP00000097402.2, ENSRNOT00000113737.2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      128880681..128884457
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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